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    Lrrc73 leucine rich repeat containing 73 [ Mus musculus (house mouse) ]

    Gene ID: 224813, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Lrrc73provided by MGI
    Official Full Name
    leucine rich repeat containing 73provided by MGI
    Primary source
    MGI:MGI:2684934
    See related
    Ensembl:ENSMUSG00000071073 AllianceGenome:MGI:2684934
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm88
    Summary
    Orthologous to human LRRC73 (leucine rich repeat containing 73). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in testis adult (RPKM 45.2), CNS E18 (RPKM 16.7) and 8 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Lrrc73 in Genome Data Viewer
    Location:
    17 C; 17 22.9 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (46564896..46568242)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (46254165..46257316)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E11645 Neighboring gene polymerase (RNA) I polypeptide C Neighboring gene Yip1 domain family, member 3 Neighboring gene tight junction associated protein 1 Neighboring gene predicted gene, 41588 Neighboring gene delta like non-canonical Notch ligand 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article
    2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    leucine-rich repeat-containing protein 73

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001111142.2 → NP_001104612.1  leucine-rich repeat-containing protein 73 isoform 1

      See identical proteins and their annotated locations for NP_001104612.1

      Status: VALIDATED

      Source sequence(s)
      AC116739
      Consensus CDS
      CCDS50123.1
      UniProtKB/TrEMBL
      B2RWC4
      Related
      ENSMUSP00000156533.2, ENSMUST00000233692.2
      Conserved Domains (2) summary
      cd00116
      Location:5 → 255
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:58 → 86
      LRR_RI; leucine-rich repeat [structural motif]

    2. NM_001417726.1 → NP_001404655.1  leucine-rich repeat-containing protein 73 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC116739
      UniProtKB/TrEMBL
      F6U1P7
      Related
      ENSMUSP00000092896.6, ENSMUST00000095262.6

    3. NM_001417727.1 → NP_001404656.1  leucine-rich repeat-containing protein 73 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC116739

    4. NM_001417728.1 → NP_001404657.1  leucine-rich repeat-containing protein 73 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC116739

    RNA

    1. NR_184566.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC116739

    2. NR_184567.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC116739

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      46564896..46568242
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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