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    Zfp984 zinc finger protein 984 [ Mus musculus (house mouse) ]

    Gene ID: 100041677, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Zfp984provided by MGI
    Official Full Name
    zinc finger protein 984provided by MGI
    Primary source
    MGI:MGI:3651978
    See related
    Ensembl:ENSMUSG00000078495 AllianceGenome:MGI:3651978
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm13157
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF616 (zinc finger protein 616). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in bladder adult (RPKM 2.5), liver E14 (RPKM 2.3) and 21 other tissues See more
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    Genomic context

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    See Zfp984 in Genome Data Viewer
    Location:
    4 E1; 4 78.54 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (147838431..147900065, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (147753974..147812229, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 pseudogene Neighboring gene predicted gene 13148 Neighboring gene STARR-positive B cell enhancer mm9_chr4:147131061-147131362 Neighboring gene STARR-positive B cell enhancer mm9_chr4:147137358-147137659 Neighboring gene STARR-positive B cell enhancer mm9_chr4:147149499-147149800 Neighboring gene STARR-positive B cell enhancer mm9_chr4:147153946-147154247 Neighboring gene STARR-positive B cell enhancer ABC_E4724 Neighboring gene STARR-positive B cell enhancer ABC_E9623 Neighboring gene STARR-positive B cell enhancer ABC_E6282 Neighboring gene STARR-seq mESC enhancer starr_12061 Neighboring gene STARR-positive B cell enhancer mm9_chr4:147185666-147185967 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:147187429-147187616 Neighboring gene STARR-positive B cell enhancer mm9_chr4:147188614-147188915 Neighboring gene ribosomal protein S19, pseudogene 3 Neighboring gene zinc finger protein 933 Neighboring gene STARR-positive B cell enhancer ABC_E4726 Neighboring gene STARR-positive B cell enhancer ABC_E181 Neighboring gene migration and invasion inhibitory protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. The Vertebrate Genome Annotation browser 10 years on. Harrow JL, et al. Nucleic Acids Res, 2014 Jan. PMID 24316575, Free PMC Article
    2. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
    3. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
    4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC100041677
    Names
    novel KRAB box domain containing protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001127189.3 → NP_001120661.1  uncharacterized protein LOC100041677

      See identical proteins and their annotated locations for NP_001120661.1

      Status: VALIDATED

      Source sequence(s)
      AL606910, AL607066
      Consensus CDS
      CCDS57314.1
      UniProtKB/TrEMBL
      A2A7A2
      Related
      ENSMUSP00000101360.4, ENSMUST00000105734.10
      Conserved Domains (4) summary
      COG5048
      Location:220 → 465
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:380 → 400
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box
      pfam13465
      Location:476 → 500
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      147838431..147900065 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036163526.1 → XP_036019419.1  uncharacterized protein LOC100041677 isoform X1

      UniProtKB/TrEMBL
      A2A7A2
      Conserved Domains (4) summary
      COG5048
      Location:220 → 465
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:380 → 400
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box
      pfam13465
      Location:476 → 500
      zf-H2C2_2; Zinc-finger double domain

    2. XM_030253010.1 → XP_030108870.1  uncharacterized protein LOC100041677 isoform X1

      UniProtKB/TrEMBL
      A2A7A2
      Conserved Domains (4) summary
      COG5048
      Location:220 → 465
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:380 → 400
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box
      pfam13465
      Location:476 → 500
      zf-H2C2_2; Zinc-finger double domain

    3. XM_030253008.1 → XP_030108868.1  uncharacterized protein LOC100041677 isoform X1

      UniProtKB/TrEMBL
      A2A7A2
      Conserved Domains (4) summary
      COG5048
      Location:220 → 465
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:380 → 400
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box
      pfam13465
      Location:476 → 500
      zf-H2C2_2; Zinc-finger double domain

    4. XM_030253006.1 → XP_030108866.1  uncharacterized protein LOC100041677 isoform X1

      UniProtKB/TrEMBL
      A2A7A2
      Conserved Domains (4) summary
      COG5048
      Location:220 → 465
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:380 → 400
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box
      pfam13465
      Location:476 → 500
      zf-H2C2_2; Zinc-finger double domain

    5. XM_030253002.1 → XP_030108862.1  uncharacterized protein LOC100041677 isoform X1

      UniProtKB/TrEMBL
      A2A7A2
      Conserved Domains (4) summary
      COG5048
      Location:220 → 465
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:380 → 400
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box
      pfam13465
      Location:476 → 500
      zf-H2C2_2; Zinc-finger double domain

    6. XM_030253001.1 → XP_030108861.1  uncharacterized protein LOC100041677 isoform X1

      UniProtKB/TrEMBL
      A2A7A2
      Conserved Domains (4) summary
      COG5048
      Location:220 → 465
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:380 → 400
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box
      pfam13465
      Location:476 → 500
      zf-H2C2_2; Zinc-finger double domain

    7. XM_036163527.1 → XP_036019420.1  uncharacterized protein LOC100041677 isoform X2

      Conserved Domains (3) summary
      COG5048
      Location:212 → 524
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:357 → 377
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box
    Nucleotide Protein Strain
    Heading Accession and Version

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