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    Csgalnact Chondroitin sulfate N-acetylgalactosaminyltransferase [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36079, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Csgalnactprovided by FlyBase
    Official Full Name
    Chondroitin sulfate N-acetylgalactosaminyltransferaseprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033500
    Locus tag
    Dmel_CG12913
    See related
    AllianceGenome:FB:FBgn0033500
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG12913; dCSGalNAcT1; Dmel\CG12913
    Summary
    Predicted to enable glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity and glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity. Involved in wound healing. Predicted to be located in Golgi cisterna membrane. Predicted to be active in Golgi apparatus. Orthologous to human CSGALNACT1 (chondroitin sulfate N-acetylgalactosaminyltransferase 1) and CSGALNACT2 (chondroitin sulfate N-acetylgalactosaminyltransferase 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Csgalnact in Genome Data Viewer
    Location:
    46F8-46F9; 2-62 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (10249220..10255495)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (6136725..6143000)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45265 Neighboring gene Histidine decarboxylase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Synaptobrevin Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR30009

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Glycosylation of proteins in plants and invertebrates. Wilson IB. Curr Opin Struct Biol, 2002 Oct. PMID 12464307
    2. Mutations of the withered (whd) gene in Drosophila melanogaster confer hypersensitivity to oxidative stress and are lesions of the carnitine palmitoyltransferase I (CPT I) gene. Strub BR, et al. Genome, 2008 Jun. PMID 18521119
    3. Genetic screen in Drosophila melanogaster uncovers a novel set of genes required for embryonic epithelial repair. Campos I, et al. Genetics, 2010 Jan. PMID 19884309, Free PMC Article
    4. Phenotype-based clustering of glycosylation-related genes by RNAi-mediated gene silencing. Yamamoto-Hino M, et al. Genes Cells, 2015 Jun. PMID 25940448, Free PMC Article
    5. Putative synaptic genes defined from a Drosophila whole body developmental transcriptome by a machine learning approach. Pazos Obregón F, et al. BMC Genomics, 2015 Sep 15. PMID 26370122, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables acetylgalactosaminyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in chondroitin sulfate biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in wound healing HMP PubMed 
    Component Evidence Code Pubs
    is_active_in Golgi apparatus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in Golgi cisterna membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    chondroitin sulfate N-acetylgalactosaminyltransferase
    Names
    CG12913-PA
    CG12913-PB
    Csgalnact-PA
    Csgalnact-PB
    NP_001286277.1
    NP_610567.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      10249220..10255495
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299348.1 → NP_001286277.1  chondroitin sulfate N-acetylgalactosaminyltransferase, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286277.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z863
      Conserved Domains (1) summary
      cl11394
      Location:59 → 521
      Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

    2. NM_136723.3 → NP_610567.1  chondroitin sulfate N-acetylgalactosaminyltransferase, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610567.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z863
      Related
      FBpp0087424
      Conserved Domains (1) summary
      cl11394
      Location:59 → 521
      Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1Z863 A1Z863

    Gene LinkOut

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