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    px plexus [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37573, updated on 4-Jan-2025

    Summary

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    Official Symbol
    pxprovided by FlyBase
    Official Full Name
    plexusprovided by FlyBase
    Primary source
    FLYBASE:FBgn0003175
    Locus tag
    Dmel_CG4444
    See related
    AllianceGenome:FB:FBgn0003175
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG4444; Dmel\CG4444; l(2)k08134; l(2)k08316; PX
    Summary
    Involved in imaginal disc-derived wing vein morphogenesis. Located in nuclear matrix. Is expressed in salivary gland; wing disc; and wing pouch. [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    all
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    Genomic context

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    Location:
    58E4-58E8; 2-100 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (22494297..22562065, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (18381802..18449570, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene gasoline Neighboring gene uncharacterized protein Neighboring gene defense repressor 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Studies on the nature and function of polygenic loci in Drosophila. II. The subthreshold wing vein pattern revealed in selection experiments. Thompson JN Jr. Heredity (Edinb), 1974 Dec. PMID 4217335
    2. The Drosophila mei-S332 gene promotes sister-chromatid cohesion in meiosis following kinetochore differentiation. Kerrebrock AW, et al. Genetics, 1992 Apr. PMID 1582560, Free PMC Article
    3. The purging of deleterious mutations in simple and complex mating environments. Colpitts J, et al. Biol Lett, 2017 Oct. PMID 29021319, Free PMC Article
    4. Constructing balancer chromosomes for genetic screens in Drosophila hydei. Hackstein JH, et al. Theor Appl Genet, 1992 Apr. PMID 24202759
    5. Wing surface interactions in venation patterning in Drosophila. Milán M, et al. Mech Dev, 1997 Oct. PMID 9392517

    See all (101) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    mobile_element

    • Loc: c22529298-22525816 mobile_element_type = transposon:jockey{}872

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in imaginal disc-derived wing vein morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in imaginal disc-derived wing vein morphogenesis TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nuclear matrix IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    plexus
    Names
    CG4444-PA
    CG4444-PB
    CG4444-PD
    CG4444-PE
    CG4444-PF
    CG4444-PG
    px-PA
    px-PB
    px-PD
    px-PE
    px-PF
    px-PG

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      22494297..22562065 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001382123.1 → NP_001369111.1  plexus, isoform F [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A6M3Q8H4, Q9U8Q0
      Conserved Domains (2) summary
      PRK14086
      Location:237 → 428
      dnaA; chromosomal replication initiator protein DnaA
      pfam05672
      Location:1429 → 1456
      MAP7; MAP7 (E-MAP-115) family

    2. NM_001382124.1 → NP_001369112.1  plexus, isoform G [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A6M3QHJ5, Q9U8Q0
      Conserved Domains (2) summary
      PRK14086
      Location:237 → 428
      dnaA; chromosomal replication initiator protein DnaA
      pfam05672
      Location:1429 → 1456
      MAP7; MAP7 (E-MAP-115) family

    3. NM_001274207.1 → NP_001261136.1  plexus, isoform E [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KGB8, Q9U8Q0
      Conserved Domains (2) summary
      pfam05672
      Location:1424 → 1456
      MAP7; MAP7 (E-MAP-115) family
      pfam13300
      Location:1426 → 1456
      DUF4078; Domain of unknown function (DUF4078)

    4. NM_166535.2 → NP_726208.1  plexus, isoform A [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U8Q0, Q9W244
      Related
      FBpp0071749
      Conserved Domains (2) summary
      pfam05672
      Location:1424 → 1456
      MAP7; MAP7 (E-MAP-115) family
      pfam13300
      Location:1426 → 1456
      DUF4078; Domain of unknown function (DUF4078)

    5. NM_001103947.2 → NP_001097417.1  plexus, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8DYM2
      Conserved Domains (2) summary
      pfam05672
      Location:964 → 996
      MAP7; MAP7 (E-MAP-115) family
      pfam13300
      Location:966 → 996
      DUF4078; Domain of unknown function (DUF4078)

    6. NM_001274206.1 → NP_001261135.1  plexus, isoform D [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KFF4
      Conserved Domains (2) summary
      pfam05672
      Location:373 → 405
      MAP7; MAP7 (E-MAP-115) family
      pfam13300
      Location:375 → 405
      DUF4078; Domain of unknown function (DUF4078)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KFF4 A0A0B4KFF4
    A0A0B4KGB8 A0A0B4KGB8
    A0A6M3Q8H4 A0A6M3Q8H4
    A0A6M3QHJ5 A0A6M3QHJ5
    A8DYM2 A8DYM2
    Q95TI5 Q95TI5
    Q9U8Q0 Q9U8Q0
    Q9W244 Q9W244

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