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    Pnrc2 proline-rich nuclear receptor coactivator 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100125373, updated on 9-Dec-2024

    Summary

    Symbol
    Pnrc2provided by RGD
    Full Name
    proline-rich nuclear receptor coactivator 2provided by RGD
    Primary source
    RGD:1642418
    See related
    EnsemblRapid:ENSRNOG00000070268 AllianceGenome:RGD:1642418
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Predicted to be located in Golgi apparatus and nucleoplasm. Predicted to be active in P-body and nucleus. Orthologous to human PNRC2 (proline rich nuclear receptor coactivator 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 814.9), Spleen (RPKM 697.8) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Pnrc2 in Genome Data Viewer
    Location:
    5q36
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (153387522..153390506, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (148103966..148106950, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (154220552..154223536, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene 60S acidic ribosomal protein P2-like Neighboring gene serine and arginine rich splicing factor 10 Neighboring gene cannabinoid receptor 2 Neighboring gene alpha-L-fucosidase 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC93828

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in P-body IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in P-body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in P-body ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    proline-rich nuclear receptor coactivator 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001103360.1NP_001096830.1  proline-rich nuclear receptor coactivator 2

      See identical proteins and their annotated locations for NP_001096830.1

      Status: PROVISIONAL

      Source sequence(s)
      BC081903
      UniProtKB/Swiss-Prot
      Q66HE1
      UniProtKB/TrEMBL
      A6IT73
      Related
      ENSRNOP00000084836.1, ENSRNOT00000104557.2
      Conserved Domains (1) summary
      pfam15365
      Location:88106
      PNRC; Proline-rich nuclear receptor coactivator motif

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      153387522..153390506 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)