Cenpq centromere protein Q [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Cenpqprovided by RGD
Official Full Name: centromere protein Qprovided by RGD
Primary source: RGD:1359451
See related: EnsemblRapid:ENSRNOG00000056226 AllianceGenome:RGD:1359451
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in metaphase chromosome alignment and positive regulation of protein localization to kinetochore. Predicted to be located in actin cytoskeleton and nucleoplasm. Predicted to be part of inner kinetochore. Predicted to be active in nucleus. Orthologous to human CENPQ (centromere protein Q). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Testes (RPKM 65.0), Thymus (RPKM 45.7) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 9q13

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	9	NC_086027.1 (27454339..27469371)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	9	NC_051344.1 (19957122..19972807)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	9	NC_005108.4 (23352271..23368774)

Chromosome 9 - NC_086027.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in metaphase chromosome alignment	IEA Inferred from Electronic Annotation more info
involved_in metaphase chromosome alignment	ISO Inferred from Sequence Orthology more info
involved_in metaphase chromosome alignment	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of protein localization to kinetochore	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of protein localization to kinetochore	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of protein localization to kinetochore	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in actin cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in actin cytoskeleton	ISO Inferred from Sequence Orthology more info
located_in chromosome, centromeric region	IEA Inferred from Electronic Annotation more info
part_of inner kinetochore	IEA Inferred from Electronic Annotation more info
part_of inner kinetochore	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: centromere protein Q

Names: CENP-Q

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.