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    SQE2 squalene epoxidase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816814, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SQE2
    Official Full Name
    squalene epoxidase 2
    Primary source
    TAIR:AT2G22830
    Locus tag
    AT2G22830
    See related
    Araport:AT2G22830
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    squalene epoxidase 2; T20K9.4; T20K9_4
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    Genomic context

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    See SQE2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    6
    Sequence:
    Chromosome: 2; NC_003071.7 (9723615..9726384, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene 1-aminocyclopropane-1-carboxylate synthase 4 Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene growth-regulating factor 1 Neighboring gene basic leucine-zipper 6 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An example of intron junctional sliding in the gene families encoding squalene monooxygenase homologues in Arabidopsis thaliana and Brassica napus. Schäfer UA, et al. Plant Mol Biol, 1999 Mar. PMID 10350086
    2. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_127848.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables squalene monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in sterol biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within sterol biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    squalene epoxidase 2
    NP_179868.1
    • squalene epoxidase 2 (SQE2); FUNCTIONS IN: squalene monooxygenase activity, electron carrier activity, oxidoreductase activity, FAD binding; INVOLVED IN: sterol biosynthetic process; LOCATED IN: integral to membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Squalene epoxidase (InterPro:IPR013698), Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal (InterPro:IPR003953); BEST Arabidopsis thaliana protein match is: squalene epoxidase 3 (TAIR:AT4G37760.1); Has 2838 Blast hits to 2834 proteins in 830 species: Archae - 46; Bacteria - 1617; Metazoa - 134; Fungi - 223; Plants - 197; Viruses - 0; Other Eukaryotes - 621 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      9723615..9726384 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127848.4 → NP_179868.1  squalene epoxidase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179868.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O81000
      UniProtKB/TrEMBL
      A0A5S9X0M5
      Conserved Domains (3) summary
      PLN02985
      Location:77 → 582
      PLN02985; squalene monooxygenase
      pfam08491
      Location:273 → 544
      SE; Squalene epoxidase
      pfam13450
      Location:127 → 154
      NAD_binding_8; NAD(P)-binding Rossmann-like domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O81000.1

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