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    CNGC8 cyclic nucleotide gated channel 8 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838566, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CNGC8
    Official Full Name
    cyclic nucleotide gated channel 8
    Primary source
    TAIR:AT1G19780
    Locus tag
    AT1G19780
    See related
    Araport:AT1G19780
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATCNGC8; cyclic nucleotide gated channel 8; cyclic nucleotide gated channel 8; F14P1.12; F14P1_12
    Summary
    Encodes a member of the cyclic nucleotide gated channel (CNGC) family that is essential for male reproductive fertility.
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    Genomic context

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    See CNGC8 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Sequence:
    Chromosome: 1; NC_003070.9 (6833669..6836633, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ATP-dependent protease La (LON) domain protein Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene purine permease 14 Neighboring gene SHI-related sequence 7 Neighboring gene trigalactosyldiacylglycerol 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cyclic nucleotide gated channels 7 and 8 are essential for male reproductive fertility. Tunc-Ozdemir M, et al. PLoS One, 2013. PMID 23424627, Free PMC Article
    2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CNGC7 and 8 are at least partially redundant and provide an essential function at the initiation of pollen tube tip growth
      Title: Cyclic nucleotide gated channels 7 and 8 are essential for male reproductive fertility.
    Submit: New GeneRIF Correction

    General gene information

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    NM_001332406.1
    NM_101834.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables monoatomic ion channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within pollen tube growth IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    cyclic nucleotide gated channel 8
    NP_173408.2
    • cyclic nucleotide gated channel 8 (CNGC8); FUNCTIONS IN: ion channel activity, cyclic nucleotide binding, calmodulin binding; INVOLVED IN: ion transport, transmembrane transport; LOCATED IN: membrane; EXPRESSED IN: petal, leaf whorl, male gametophyte, flower, pollen tube; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Cyclic nucleotide-binding (InterPro:IPR000595), Ion transport (InterPro:IPR005821), Cyclic nucleotide-binding-like (InterPro:IPR018490), RmlC-like jelly roll fold (InterPro:IPR014710), IQ calmodulin-binding region (InterPro:IPR000048); BEST Arabidopsis thaliana protein match is: cyclic nucleotide gated channel 7 (TAIR:AT1G15990.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      6833669..6836633 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101834.4 → NP_173408.2  cyclic nucleotide gated channel 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173408.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FXH6
      UniProtKB/TrEMBL
      A0A5S9V964
      Conserved Domains (3) summary
      COG0664
      Location:502 → 637
      Crp; cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]
      cd00038
      Location:508 → 639
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
      pfam00520
      Location:150 → 437
      Ion_trans; Ion transport protein

    2. NM_001332406.1 → NP_001323012.1  cyclic nucleotide gated channel 8 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AVR5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FXH6.2

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