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    Major facilitator superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838529, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Major facilitator superfamily protein
    Primary source
    TAIR:AT1G19450
    Locus tag
    AT1G19450
    See related
    Araport:AT1G19450
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F18O14.22; F18O14_22
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    17
    Sequence:
    Chromosome: 1; NC_003070.9 (6731411..6735024, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene 3-ketoacyl-CoA synthase 4 Neighboring gene Galactose oxidase/kelch repeat superfamily protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Vacuolar sugar transporter EARLY RESPONSE TO DEHYDRATION6-LIKE4 affects fructose signaling and plant growth. Khan A, et al. Plant Physiol, 2023 Oct 26. PMID 37427783
    2. Uncovering Arabidopsis membrane protein interactome enriched in transporters using mating-based split ubiquitin assays and classification models. Chen J, et al. Front Plant Sci, 2012. PMID 22737156, Free PMC Article
    3. The vegetative vacuole proteome of Arabidopsis thaliana reveals predicted and unexpected proteins. Carter C, et al. Plant Cell, 2004 Dec. PMID 15539469, Free PMC Article
    4. A proteomics dissection of Arabidopsis thaliana vacuoles isolated from cell culture. Jaquinod M, et al. Mol Cell Proteomics, 2007 Mar. PMID 17151019, Free PMC Article
    5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_101801.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables carbohydrate transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables sugar transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within fructose transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plant-type vacuole HDA PubMed 
    located_in plant-type vacuole membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Major facilitator superfamily protein
    NP_173377.1
    • Major facilitator superfamily protein; FUNCTIONS IN: carbohydrate transmembrane transporter activity, sugar:hydrogen symporter activity; INVOLVED IN: transport, transmembrane transport; LOCATED IN: plasma membrane, vacuole, membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Sugar transporter, conserved site (InterPro:IPR005829), Major facilitator superfamily (InterPro:IPR020846), General substrate transporter (InterPro:IPR005828), Sugar/inositol transporter (InterPro:IPR003663), Major facilitator superfamily, general substrate transporter (InterPro:IPR016196); BEST Arabidopsis thaliana protein match is: Major facilitator superfamily protein (TAIR:AT1G75220.1); Has 32354 Blast hits to 31683 proteins in 2302 species: Archae - 652; Bacteria - 16202; Metazoa - 5205; Fungi - 6407; Plants - 2489; Viruses - 2; Other Eukaryotes - 1397 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      6731411..6735024 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101801.3 → NP_173377.1  Major facilitator superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173377.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q93YP9, Q9LN48
      UniProtKB/TrEMBL
      A0A178WCB9, A0A5S9V5S6, A0A654EG97
      Conserved Domains (1) summary
      cd17358
      Location:50 → 482
      MFS_GLUT6_8_Class3_like; Glucose transporter (GLUT) types 6 and 8, Class 3 GLUTs, and similar transporters of the Major Facilitator Superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q93YP9.1

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