NTF2B nuclear transport factor 2B [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: NTF2B
Official Full Name: nuclear transport factor 2B
Primary source: TAIR:AT1G27970
Locus tag: AT1G27970
See related: Araport:AT1G27970
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F13K9.26; F13K9_26; nuclear transport factor 2B
Summary: Encodes an ortholog of yeast NTF2, a nuclear envelop transport protein that functions as the nuclear import receptor for RanGDP, an essential player in nucleocytoplasmic transport.
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Genomic context

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See NTF2B in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 3

Sequence:: Chromosome: 1; NC_003070.9 (9746709..9748467)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_001084143.2

Supported by ESTs:

NM_102562.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables small GTPase binding	IGI Inferred from Genetic Interaction more info	PubMed
enables small GTPase binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within nucleocytoplasmic transport	IGI Inferred from Genetic Interaction more info	PubMed
involved_in protein import into nucleus	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within protein import into nucleus	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	ISM Inferred from Sequence Model more info
located_in cytoplasmic stress granule	IDA Inferred from Direct Assay more info	PubMed
located_in cytosol	HDA more info	PubMed
located_in nuclear envelope	IDA Inferred from Direct Assay more info	PubMed
NOT located_in nucleolus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	HDA more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	HDA more info	PubMed

General protein information

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Preferred Names: nuclear transport factor 2B

NP_001077612.1

nuclear transport factor 2B (NTF2B); FUNCTIONS IN: protein transporter activity, Ran GTPase binding; INVOLVED IN: nucleocytoplasmic transport, protein import into nucleus; LOCATED IN: nuclear envelope, intracellular, nucleus, plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Nuclear transport factor 2 (InterPro:IPR002075), Nuclear transport factor 2, Eukaryote (InterPro:IPR018222); BEST Arabidopsis thaliana protein match is: nuclear transport factor 2A (TAIR:AT1G27310.1); Has 947 Blast hits to 947 proteins in 223 species: Archae - 0; Bacteria - 0; Metazoa - 435; Fungi - 217; Plants - 201; Viruses - 0; Other Eukaryotes - 94 (source: NCBI BLink).

NP_174118.1

nuclear transport factor 2B (NTF2B); FUNCTIONS IN: protein transporter activity, Ran GTPase binding; INVOLVED IN: nucleocytoplasmic transport, protein import into nucleus; LOCATED IN: nuclear envelope, intracellular, nucleus, plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Nuclear transport factor 2 (InterPro:IPR002075), Nuclear transport factor 2, Eukaryote (InterPro:IPR018222); BEST Arabidopsis thaliana protein match is: nuclear transport factor 2A (TAIR:AT1G27310.1); Has 1018 Blast hits to 1018 proteins in 227 species: Archae - 0; Bacteria - 0; Metazoa - 491; Fungi - 232; Plants - 204; Viruses - 0; Other Eukaryotes - 91 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

9746709..9748467

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_102562.4 → NP_174118.1 nuclear transport factor 2B [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_174118.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q1H566, Q9C7F5

UniProtKB/TrEMBL

A0A178W1S4, A0A5S9W4G0, Q8LC75

Conserved Domains (1) summary

cd00780
Location:5 → 125

NTF2; Nuclear transport factor 2 (NTF2) domain plays an important role in the trafficking of macromolecules, ions and small molecules between the cytoplasm and nucleus. This bi-directional transport of macromolecules across the nuclear envelope requires many ...
NM_001084143.2 → NP_001077612.1 nuclear transport factor 2B [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_001077612.1

Status: REVIEWED

UniProtKB/TrEMBL

A8MS55, Q8LC75

Conserved Domains (1) summary

cd00780
Location:5 → 121

NTF2; Nuclear transport factor 2 (NTF2) domain plays an important role in the trafficking of macromolecules, ions and small molecules between the cytoplasm and nucleus. This bi-directional transport of macromolecules across the nuclear envelope requires many ...