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    MES17 methyl esterase 17 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820257, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MES17
    Official Full Name
    methyl esterase 17
    Primary source
    TAIR:AT3G10870
    Locus tag
    AT3G10870
    See related
    Araport:AT3G10870
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA METHYL ESTERASE 17; ATMES17; methyl esterase 17
    Summary
    Encodes a methyl IAA esterase. Methyl IAA is believed to be an inactive form of auxin that needs to be demethylated to exert a biological effect. MES17 does not act on methyl JA, MeSA, MeGA4, or MEGA9 in vitro. This gene is expressed in several tissues of seedlings and adult plants, with a higher relative level of expression in the seedling shoot apex and the adult stem.
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    Genomic context

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    See MES17 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    4
    Sequence:
    Chromosome: 3; NC_003074.8 (3400824..3402776, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene RNA-binding (RRM/RBD/RNP motifs) family protein Neighboring gene Metallo-hydrolase/oxidoreductase superfamily protein Neighboring gene Cytochrome b-c1 complex, subunit 8 protein Neighboring gene tropomyosin Neighboring gene Glycosyl hydrolase superfamily protein Neighboring gene Glycosyl hydrolase superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Inactive methyl indole-3-acetic acid ester can be hydrolyzed and activated by several esterases belonging to the AtMES esterase family of Arabidopsis. Yang Y, et al. Plant Physiol, 2008 Jul. PMID 18467465, Free PMC Article
    2. Extensive signal integration by the phytohormone protein network. Altmann M, et al. Nature, 2020 Jul. PMID 32612234
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_111924.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables hydrolase activity, acting on ester bonds IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables methyl indole-3-acetate esterase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within indoleacetic acid conjugate metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within shoot system development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    methyl esterase 17
    NP_187698.1
    • methyl esterase 17 (MES17); CONTAINS InterPro DOMAIN/s: Alpha/beta hydrolase fold-1 (InterPro:IPR000073); BEST Arabidopsis thaliana protein match is: methyl esterase 18 (TAIR:AT5G58310.1); Has 1383 Blast hits to 1383 proteins in 290 species: Archae - 0; Bacteria - 591; Metazoa - 1; Fungi - 15; Plants - 599; Viruses - 2; Other Eukaryotes - 175 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      3400824..3402776 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111924.3 → NP_187698.1  methyl esterase 17 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187698.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SG92
      UniProtKB/TrEMBL
      A0A178V796, A0A5S9XBJ3
      Conserved Domains (2) summary
      PLN02211
      Location:1 → 276
      PLN02211; methyl indole-3-acetate methyltransferase
      cl21494
      Location:20 → 273
      Abhydrolase; alpha/beta hydrolases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SG92.1

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