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    SDG4 SET domain group 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829210, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SDG4
    Official Full Name
    SET domain group 4
    Primary source
    TAIR:AT4G30860
    Locus tag
    AT4G30860
    See related
    Araport:AT4G30860
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ASH1-related 3; ASH1-RELATED 3; ASHR3; F6I18.230; F6I18_230; SET domain group 4
    Summary
    Encodes a member of the trxG protein family. Contains a SET domain which is known to be involved in modification of histone tails by methylation. Interacts physically with AMS, but the implications of this interaction are unknown.Overexpression results in plieotrophic developmental defects.
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    Genomic context

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    See SDG4 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    11
    Sequence:
    Chromosome: 4; NC_003075.7 (15024444..15027672)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene DNA-directed RNA polymerase subunit beta Neighboring gene heptahelical transmembrane protein2 Neighboring gene Restriction endonuclease, type II-like superfamily protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis SDG4 contributes to the regulation of pollen tube growth by methylation of histone H3 lysines 4 and 36 in mature pollen. Cartagena JA, et al. Dev Biol, 2008 Mar 15. PMID 18252252
    2. The Arabidopsis SET-domain protein ASHR3 is involved in stamen development and interacts with the bHLH transcription factor ABORTED MICROSPORES (AMS). Thorstensen T, et al. Plant Mol Biol, 2008 Jan. PMID 17978851
    3. Extensive signal integration by the phytohormone protein network. Altmann M, et al. Nature, 2020 Jul. PMID 32612234
    4. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    5. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_119233.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    NOT enables histone methyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    SET domain group 4
    NP_567859.1
    • SET domain group 4 (SDG4); CONTAINS InterPro DOMAIN/s: SET domain (InterPro:IPR001214), Zinc finger, PHD-type, conserved site (InterPro:IPR019786), Zinc finger, PHD-type (InterPro:IPR001965), Post-SET domain (InterPro:IPR003616), Zinc finger, FYVE/PHD-type (InterPro:IPR011011), AWS (InterPro:IPR006560); BEST Arabidopsis thaliana protein match is: histone-lysine N-methyltransferase ASHH3 (TAIR:AT2G44150.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      15024444..15027672
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119233.2 → NP_567859.1  SET domain group 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567859.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O65563, Q949T8
      UniProtKB/TrEMBL
      A0A178UX33, A0A654FUG2
      Conserved Domains (3) summary
      smart00570
      Location:286 → 326
      AWS; associated with SET domains
      cd15565
      Location:121 → 167
      PHD2_NSD; PHD finger 2 found in nuclear receptor-binding SET domain-containing (NSD) proteins
      cd19175
      Location:327 → 465
      SET_ASHR3-like; SET domain (including post-SET domain) found in Arabidopsis thaliana ASH1-related protein 3 (ASHR3) and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q949T8.1

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