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    ASP5 aspartate aminotransferase 5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829330, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ASP5
    Official Full Name
    aspartate aminotransferase 5
    Primary source
    TAIR:AT4G31990
    Locus tag
    AT4G31990
    See related
    Araport:AT4G31990
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AAT3; ASPARTATE AMINOTRANSFERASE; aspartate aminotransferase 5; ASPARTATE AMINOTRANSFERASE DEFICIENT 3; ATAAT1; F11C18.15
    Summary
    Encodes a plastid-localized aspartate aminotransferase. Does not display any PAT (glutamate/aspartate-prephenate aminotransferase) activity even in the presence of a high concentration of prephenate.
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    Genomic context

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    See ASP5 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    12
    Sequence:
    Chromosome: 4; NC_003075.7 (15470744..15473885, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene PPPDE thiol peptidase family protein Neighboring gene ncRNA Neighboring gene Ribosomal protein L39 family protein Neighboring gene Protein kinase superfamily protein Neighboring gene ncRNA Neighboring gene HSI2-like 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isolation, characterisation and expression of a cDNA clone encoding plastid aspartate aminotransferase from Arabidopsis thaliana. Wilkie SE, et al. Plant Mol Biol, 1995 Mar. PMID 7766905
    2. Identification of a plant gene encoding glutamate/aspartate-prephenate aminotransferase: the last homeless enzyme of aromatic amino acids biosynthesis. Graindorge M, et al. FEBS Lett, 2010 Oct 22. PMID 20883697
    3. Recombinant expression, purification, and characterization of three isoenzymes of aspartate aminotransferase from Arabidopsis thaliana. Wilkie SE, et al. Protein Expr Purif, 1998 Apr. PMID 9535706
    4. Identification and molecular properties of SUMO-binding proteins in Arabidopsis. Park HC, et al. Mol Cells, 2011 Aug. PMID 21607647, Free PMC Article
    5. The chloroplast lumen and stromal proteomes of Arabidopsis thaliana show differential sensitivity to short- and long-term exposure to low temperature. Goulas E, et al. Plant J, 2006 Sep. PMID 16923014

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001036690.1
    NM_001203956.1
    NM_119351.3
    NM_179152.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables L-aspartate:2-oxoglutarate aminotransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables L-aspartate:2-oxoglutarate aminotransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables L-aspartate:2-oxoglutarate aminotransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    NOT enables aspartate-prephenate aminotransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    NOT enables glutamate-prephenate aminotransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in 2-oxoglutarate metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in amino acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in aspartate metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in glutamate metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_or_within response to cold IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apoplast HDA PubMed 
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast envelope HDA PubMed 
    located_in chloroplast stroma HDA PubMed 
    NOT located_in cytosol RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plastid IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in stromule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    aspartate aminotransferase 5
    NP_001031767.1
    • aspartate aminotransferase 5 (ASP5); FUNCTIONS IN: L-aspartate:2-oxoglutarate aminotransferase activity; INVOLVED IN: response to cadmium ion, response to cold; LOCATED IN: apoplast, stromule, chloroplast, plastid; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Aminotransferase, class I/classII (InterPro:IPR004839), Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Aminotransferases, class-I, pyridoxal-phosphate-binding site (InterPro:IPR004838), Aspartate/other aminotransferase (InterPro:IPR000796), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421); BEST Arabidopsis thaliana protein match is: aspartate aminotransferase 3 (TAIR:AT5G11520.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_001190885.1
    • aspartate aminotransferase 5 (ASP5); CONTAINS InterPro DOMAIN/s: Aminotransferase, class I/classII (InterPro:IPR004839), Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Aminotransferases, class-I, pyridoxal-phosphate-binding site (InterPro:IPR004838), Aspartate/other aminotransferase (InterPro:IPR000796), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421); BEST Arabidopsis thaliana protein match is: aspartate aminotransferase 3 (TAIR:AT5G11520.1).
    NP_194927.1
    • aspartate aminotransferase 5 (ASP5); FUNCTIONS IN: L-aspartate:2-oxoglutarate aminotransferase activity; INVOLVED IN: response to cadmium ion, response to cold; LOCATED IN: in 6 components; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Aminotransferase, class I/classII (InterPro:IPR004839), Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Aminotransferases, class-I, pyridoxal-phosphate-binding site (InterPro:IPR004838), Aspartate/other aminotransferase (InterPro:IPR000796), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421); BEST Arabidopsis thaliana protein match is: aspartate aminotransferase 3 (TAIR:AT5G11520.1); Has 5538 Blast hits to 5532 proteins in 1319 species: Archae - 6; Bacteria - 3683; Metazoa - 482; Fungi - 406; Plants - 379; Viruses - 0; Other Eukaryotes - 582 (source: NCBI BLink).
    NP_849483.1
    • aspartate aminotransferase 5 (ASP5); FUNCTIONS IN: L-aspartate:2-oxoglutarate aminotransferase activity; INVOLVED IN: response to cadmium ion, response to cold; LOCATED IN: apoplast, stromule, chloroplast, plastid, chloroplast envelope; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Aminotransferase, class I/classII (InterPro:IPR004839), Aminotransferases, class-I, pyridoxal-phosphate-binding site (InterPro:IPR004838), Aspartate/other aminotransferase (InterPro:IPR000796), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421); BEST Arabidopsis thaliana protein match is: aspartate aminotransferase 3 (TAIR:AT5G11520.1); Has 5538 Blast hits to 5532 proteins in 1319 species: Archae - 6; Bacteria - 3683; Metazoa - 482; Fungi - 406; Plants - 379; Viruses - 0; Other Eukaryotes - 582 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      15470744..15473885 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_179152.3 → NP_849483.1  aspartate aminotransferase 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849483.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49392, P46248, Q8LGE6
      UniProtKB/TrEMBL
      A0A178V5X1, A0A384KDZ4, A0A5S9XXS5, B9DGA8
      Conserved Domains (1) summary
      PLN02397
      Location:30 → 453
      PLN02397; aspartate transaminase

    2. NM_001203956.1 → NP_001190885.1  aspartate aminotransferase 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190885.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9XXS5, F4JTH0
      Conserved Domains (2) summary
      PLN02397
      Location:30 → 448
      PLN02397; aspartate transaminase
      pfam00155
      Location:74 → 440
      Aminotran_1_2; Aminotransferase class I and II

    3. NM_001036690.1 → NP_001031767.1  aspartate aminotransferase 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031767.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9XXS5, B9DG21
      Conserved Domains (2) summary
      PLN02397
      Location:30 → 452
      PLN02397; aspartate transaminase
      pfam00155
      Location:79 → 445
      Aminotran_1_2; Aminotransferase class I and II

    4. NM_119351.3 → NP_194927.1  aspartate aminotransferase 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194927.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49392, P46248, Q8LGE6
      UniProtKB/TrEMBL
      A0A178V5X1, A0A384KDZ4, A0A5S9XXS5, B9DGA8
      Conserved Domains (1) summary
      PLN02397
      Location:30 → 453
      PLN02397; aspartate transaminase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P46248.2

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