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    PUB14 plant U-box 14 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824650, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PUB14
    Official Full Name
    plant U-box 14
    Primary source
    TAIR:AT3G54850
    Locus tag
    AT3G54850
    See related
    Araport:AT3G54850
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATPUB14; plant U-box 14
    Summary
    Encodes a protein with a typical U-box domain followed by an Armadillo repeat region, a domain organization that is frequently found in plant U-box proteins. Displays ubiquitin ligase activity in vitro.
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    Genomic context

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    See PUB14 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    4
    Sequence:
    Chromosome: 3; NC_003074.8 (20321353..20324020)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Ras-related small GTP-binding family protein Neighboring gene Sec1/munc18-like (SM) proteins superfamily Neighboring gene Armadillo/beta-catenin repeat family protein / kinesin motor family protein Neighboring gene zinc finger protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure and biochemical function of a prototypical Arabidopsis U-box domain. Andersen P, et al. J Biol Chem, 2004 Sep 17. PMID 15231834
    2. A Decoy Library Uncovers U-Box E3 Ubiquitin Ligases That Regulate Flowering Time in Arabidopsis. Feke AM, et al. Genetics, 2020 Jul. PMID 32434795, Free PMC Article
    3. PAH-domain-specific interactions of the Arabidopsis transcription coregulator SIN3-LIKE1 (SNL1) with telomere-binding protein 1 and ALWAYS EARLY2 Myb-DNA binding factors. Bowen AJ, et al. J Mol Biol, 2010 Feb 5. PMID 19962994
    4. Interactions between the S-domain receptor kinases and AtPUB-ARM E3 ubiquitin ligases suggest a conserved signaling pathway in Arabidopsis. Samuel MA, et al. Plant Physiol, 2008 Aug. PMID 18552232, Free PMC Article
    5. Extensive signal integration by the phytohormone protein network. Altmann M, et al. Nature, 2020 Jul. PMID 32612234

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A Decoy Library Uncovers U-Box E3 Ubiquitin Ligases That Regulate Flowering Time in Arabidopsis.
      Title: A Decoy Library Uncovers U-Box E3 Ubiquitin Ligases That Regulate Flowering Time in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    NM_115342.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transmembrane receptor protein serine/threonine kinase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables ubiquitin-protein transferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein ubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    plant U-box 14
    NP_191045.2
    • plant U-box 14 (PUB14); FUNCTIONS IN: ubiquitin-protein ligase activity; INVOLVED IN: protein ubiquitination; LOCATED IN: ubiquitin ligase complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: U box domain (InterPro:IPR003613), Armadillo-like helical (InterPro:IPR011989), Armadillo (InterPro:IPR000225), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: plant U-box 13 (TAIR:AT3G46510.1); Has 7501 Blast hits to 4963 proteins in 297 species: Archae - 2; Bacteria - 29; Metazoa - 1804; Fungi - 795; Plants - 4036; Viruses - 3; Other Eukaryotes - 832 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      20321353..20324020
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_115342.5 → NP_191045.2  plant U-box 14 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_191045.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8VZ40, Q9SV34
      UniProtKB/TrEMBL
      A0A178V9F4, A0A5S9XKW0, A0A7G2ESZ4
      Conserved Domains (3) summary
      smart00504
      Location:251 → 314
      Ubox; Modified RING finger domain
      PLN03200
      Location:336 → 579
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:380 → 416
      ARM; armadillo repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VZ40.1

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