GPX5 glutathione peroxidase 5 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: GPX5
Official Full Name: glutathione peroxidase 5
Primary source: TAIR:AT3G63080
Locus tag: AT3G63080
See related: Araport:AT3G63080
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATGPX5; glutathione peroxidase 5; maternal effect embryo arrest 42; MEE42
Summary: Encodes glutathione peroxidase.
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Genomic context

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See GPX5 in Genome Data Viewer

Location:: chromosome: 3

Exon count:: 6

Sequence:: Chromosome: 3; NC_003074.8 (23309737..23311397)

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_116173.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables glutathione peroxidase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within embryo development ending in seed dormancy	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to oxidative stress	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in cytosol	HDA more info	PubMed
located_in endomembrane system	IDA Inferred from Direct Assay more info	PubMed
located_in endoplasmic reticulum	ISS Inferred from Sequence or Structural Similarity more info	PubMed
located_in plasma membrane	HDA more info	PubMed

General protein information

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Preferred Names: glutathione peroxidase 5

NP_191867.1

glutathione peroxidase 5 (GPX5); FUNCTIONS IN: glutathione peroxidase activity; INVOLVED IN: N-terminal protein myristoylation, embryo development ending in seed dormancy; LOCATED IN: endoplasmic reticulum, plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Thioredoxin-like fold (InterPro:IPR012336), Glutathione peroxidase (InterPro:IPR000889); BEST Arabidopsis thaliana protein match is: glutathione peroxidase 4 (TAIR:AT2G48150.1); Has 7302 Blast hits to 7301 proteins in 1728 species: Archae - 2; Bacteria - 3480; Metazoa - 788; Fungi - 210; Plants - 381; Viruses - 8; Other Eukaryotes - 2433 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003074.8 Reference assembly

Range

23309737..23311397

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_116173.4 → NP_191867.1 glutathione peroxidase 5 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_191867.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9LYB4

UniProtKB/TrEMBL

A0A5S9XNJ1, A0A654FKA5

Conserved Domains (1) summary

cd00340
Location:14 → 165

GSH_Peroxidase; Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per ...