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    GLR2.5 glutamate receptor 2.5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830991, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GLR2.5
    Official Full Name
    glutamate receptor 2.5
    Primary source
    TAIR:AT5G11210
    Locus tag
    AT5G11210
    See related
    Araport:AT5G11210
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA GLU; ATGLR2.5; F2I11.100; F2I11_100; glutamate receptor 2.5
    Summary
    member of Putative ligand-gated ion channel subunit family
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    Genomic context

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    See GLR2.5 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    4
    Sequence:
    Chromosome: 5; NC_003076.8 (3571020..3574817, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene glutamate receptor 2.6 Neighboring gene ncRNA Neighboring gene Integrase-type DNA-binding superfamily protein Neighboring gene DEAD/DEAH box RNA helicase family protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene tRNA-Gly

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The identity of plant glutamate receptors. Lacombe B, et al. Science, 2001 May 25. PMID 11379626
    2. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001343162.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables calcium channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables glutamate receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables intracellularly ligand-gated monoatomic ion channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables ligand-gated monoatomic ion channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in calcium ion transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in calcium-mediated signaling ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in cellular response to amino acid stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_or_within intracellular calcium ion homeostasis NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within response to light stimulus NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    glutamate receptor 2.5
    NP_001318537.1
    • glutamate receptor 2.5 (GLR2.5); FUNCTIONS IN: intracellular ligand-gated ion channel activity; INVOLVED IN: cellular calcium ion homeostasis, response to light stimulus; LOCATED IN: integral to membrane, membrane; EXPRESSED IN: stem, stamen; EXPRESSED DURING: 4 anthesis; CONTAINS InterPro DOMAIN/s: Extracellular solute-binding protein, family 3 (InterPro:IPR001638), Ionotropic glutamate receptor (InterPro:IPR001320), Extracellular ligand-binding receptor (InterPro:IPR001828), Glutamate receptor-related (InterPro:IPR015683), GPCR, family 3 (InterPro:IPR000337), Ionotropic glutamate-like receptor, plant (InterPro:IPR017103); BEST Arabidopsis thaliana protein match is: glutamate receptor 2.6 (TAIR:AT5G11180.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      3571020..3574817 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001343165.1 → NP_001332216.1  glutamate receptor 2.5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BGA4, M4GUZ8

    2. NM_001343166.1 → NP_001332215.1  glutamate receptor 2.5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BG88, M4GUZ8

    3. NM_001343168.1 → NP_001332219.1  glutamate receptor 2.5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4JWF9, Q9LFN5
      UniProtKB/TrEMBL
      A0A7G2F904

    4. NM_001343167.1 → NP_001332220.1  glutamate receptor 2.5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BGA4, M4GUZ8

    5. NM_001343163.1 → NP_001332222.1  glutamate receptor 2.5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BGA1, M4GUZ8

    6. NM_001343172.1 → NP_001332213.1  glutamate receptor 2.5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178U9J6, A0A1P8BGA6

    7. NM_001343171.1 → NP_001332214.1  glutamate receptor 2.5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BG81, M4GUZ8

    8. NM_001343170.1 → NP_001332217.1  glutamate receptor 2.5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BGB4, M4GUZ8

    9. NM_001343169.1 → NP_001332218.1  glutamate receptor 2.5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BGB4, M4GUZ8

    10. NM_001343164.1 → NP_001332221.1  glutamate receptor 2.5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      M4GWA7

    11. NM_001343162.1 → NP_001318537.1  glutamate receptor 2.5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654G0J0, A0A7G2F904
      Conserved Domains (3) summary
      cd13686
      Location:398 → 748
      GluR_Plant; Plant glutamate receptor domain; the type 2 periplasmic binding protein fold
      pfam00060
      Location:528 → 780
      Lig_chan; Ligand-gated ion channel
      cd19990
      Location:1 → 363
      PBP1_GABAb_receptor_plant; periplasmic ligand-binding domain of Arabidopsis thaliana glutamate receptors and its close homologs in other plants
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LFN5.2

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