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    Cxcl14 C-X-C motif chemokine ligand 14 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 306748, updated on 27-Nov-2024

    Summary

    Official Symbol
    Cxcl14provided by RGD
    Official Full Name
    C-X-C motif chemokine ligand 14provided by RGD
    Primary source
    RGD:1307406
    See related
    EnsemblRapid:ENSRNOG00000011984 AllianceGenome:RGD:1307406
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    BRAK
    Summary
    Predicted to enable chemokine activity. Predicted to be involved in antimicrobial humoral immune response mediated by antimicrobial peptide and killing of cells of another organism. Predicted to act upstream of or within inner ear development; negative regulation of myoblast differentiation; and positive regulation of natural killer cell chemotaxis. Predicted to be located in Golgi apparatus. Orthologous to human CXCL14 (C-X-C motif chemokine ligand 14). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Muscle (RPKM 102.7), Adrenal (RPKM 101.4) and 8 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Cxcl14 in Genome Data Viewer
    Location:
    17p14
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (8323150..8331176)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (8317930..8325956)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (9109731..9117754)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108348502 Neighboring gene uncharacterized LOC134482671 Neighboring gene U6 spliceosomal RNA Neighboring gene ribosomal protein L35, pseudogene 1 Neighboring gene neurogenin 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General protein information

    Preferred Names
    C-X-C motif chemokine 14
    Names
    chemokine (C-X-C motif) ligand 14

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013137.3NP_001013155.1  C-X-C motif chemokine 14 precursor

      See identical proteins and their annotated locations for NP_001013155.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      D4A5S7, Q8K453
      Related
      ENSRNOP00000111202.1, ENSRNOT00000169308.1
      Conserved Domains (1) summary
      pfam00048
      Location:3386
      IL8; Small cytokines (intecrine/chemokine), interleukin-8 like

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      8323150..8331176
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)