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    Il9 interleukin 9 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 116558, updated on 27-Nov-2024

    Summary

    Official Symbol
    Il9provided by RGD
    Official Full Name
    interleukin 9provided by RGD
    Primary source
    RGD:620049
    See related
    EnsemblRapid:ENSRNOG00000012131 AllianceGenome:RGD:620049
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Enables cytokine activity and interleukin-9 receptor binding activity. Involved in positive regulation of cell growth. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in asthma and respiratory syncytial virus infectious disease. Orthologous to human IL9 (interleukin 9). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Testes (RPKM 6.4) and Thymus (RPKM 1.0) See more
    Orthologs
    NEW
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    Genomic context

    See Il9 in Genome Data Viewer
    Location:
    17p14
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (8117028..8120151)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (8111772..8114895)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (8558827..8561950)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene leukocyte cell-derived chemotaxin 2 Neighboring gene F-box and leucine-rich repeat protein 21 Neighboring gene solute carrier family 25, member 48 Neighboring gene predicted gene 3045 like Neighboring gene uncharacterized LOC108348502

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables cytokine activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables cytokine activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables cytokine activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables interleukin-9 receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables interleukin-9 receptor binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105747.1NP_001099217.1  interleukin-9 precursor

      See identical proteins and their annotated locations for NP_001099217.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474032
      UniProtKB/TrEMBL
      A6KAN0, D4A8I9
      Related
      ENSRNOP00000016187.2, ENSRNOT00000016187.4

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      8117028..8120151
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)