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    senp3a SUMO specific peptidase 3a [ Danio rerio (zebrafish) ]

    Gene ID: 564950, updated on 9-Dec-2024

    Summary

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    Official Symbol
    senp3aprovided by ZNC
    Official Full Name
    SUMO specific peptidase 3aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-2303
    See related
    Ensembl:ENSDARG00000095538 AllianceGenome:ZFIN:ZDB-GENE-030131-2303
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc03g04; wu:fc03g04
    Summary
    Predicted to enable deSUMOylase activity. Predicted to be involved in protein desumoylation. Predicted to act upstream of or within proteolysis. Predicted to be located in nucleolus. Predicted to be active in nucleus. Orthologous to human SENP3 (SUMO specific peptidase 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See senp3a in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (24220157..24231139, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (23716357..23727339, complement)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene SRY-box transcription factor 19a Neighboring gene eukaryotic translation initiation factor 4A1B Neighboring gene phospholipid scramblase 3a Neighboring gene PHD finger protein 23a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Comparative genomic and expression analysis of group B1 sox genes in zebrafish indicates their diversification during vertebrate evolution. Okuda Y, et al. Dev Dyn, 2006 Mar. PMID 16408288
    2. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables cysteine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables deSUMOylase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein desumoylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    sentrin-specific protease 3a
    Names
    SUMO1/sentrin/SMT3 specific peptidase 3a

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105114.1 → NP_001098584.1  sentrin-specific protease 3a

      Status: PROVISIONAL

      Source sequence(s)
      BX119902
      UniProtKB/TrEMBL
      A0A8M1NEK6, A2BEN4
      Related
      ENSDARP00000114111.1, ENSDART00000143492.2
      Conserved Domains (1) summary
      pfam02902
      Location:361 → 533
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      24220157..24231139 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021476275.2 → XP_021331950.1  sentrin-specific protease 3a isoform X1

      UniProtKB/TrEMBL
      A0A8M9QE82
      Conserved Domains (1) summary
      cl23802
      Location:361 → 482
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394575.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      236686..247668 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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