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    xpo1b exportin 1 (CRM1 homolog, yeast) b [ Danio rerio (zebrafish) ]

    Gene ID: 561138, updated on 4-Jan-2025

    Summary

    Official Symbol
    xpo1bprovided by ZNC
    Official Full Name
    exportin 1 (CRM1 homolog, yeast) bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-070530-6
    See related
    Ensembl:ENSDARG00000063229 AllianceGenome:ZFIN:ZDB-GENE-070530-6
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    xpo1
    Summary
    Predicted to enable nuclear export signal receptor activity. Acts upstream of or within response to yeast. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in colorectal cancer; gastric adenocarcinoma; hepatocellular carcinoma; and lung non-small cell carcinoma. Orthologous to human XPO1 (exportin 1). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
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    Genomic context

    See xpo1b in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (23966258..23987581)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (23946116..23969180)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene peroxisomal biogenesis factor 13 Neighboring gene SANT and BTB domain regulator of CSR Neighboring gene si:ch211-63b16.4 Neighboring gene UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables nuclear export signal receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables nuclear export signal receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within protein export from nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein export from nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within response to yeast IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in ribosomal large subunit export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ribosomal small subunit export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      23966258..23987581
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009293053.4XP_009291328.1  exportin-1

      See identical proteins and their annotated locations for XP_009291328.1

      UniProtKB/TrEMBL
      A0A8M9PPG9, E7FBU7, X1WEG0
      Related
      ENSDARP00000128611.1, ENSDART00000154823.3
      Conserved Domains (1) summary
      cl26694
      Location:151049
      Xpo1; Exportin 1-like protein