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    vps37a VPS37A subunit of ESCRT-I [ Danio rerio (zebrafish) ]

    Gene ID: 336368, updated on 9-Dec-2024

    Summary

    Official Symbol
    vps37aprovided by ZNC
    Official Full Name
    VPS37A subunit of ESCRT-Iprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-8312
    See related
    Ensembl:ENSDARG00000017119 AllianceGenome:ZFIN:ZDB-GENE-030131-8312
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fb08f03; fj42c03; zgc:73244; zgc:77637; wu:fb08f03; wu:fj42c03
    Summary
    Acts upstream of or within locomotory behavior. Predicted to be located in late endosome membrane. Predicted to be part of ESCRT I complex. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 53. Orthologous to human VPS37A (VPS37A subunit of ESCRT-I). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See vps37a in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (16463079..16480213)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (15770142..15787276)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U3 Neighboring gene serine/threonine-protein kinase VRK1-like Neighboring gene uncharacterized LOC110439786 Neighboring gene myotubularin related protein 7b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within locomotory behavior IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein targeting to membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein targeting to vacuole IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of ESCRT I complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in late endosome membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    vacuolar protein sorting-associated protein 37A
    Names
    vacuolar protein sorting 37A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199990.1NP_956284.1  vacuolar protein sorting-associated protein 37A

      See identical proteins and their annotated locations for NP_956284.1

      Status: PROVISIONAL

      Source sequence(s)
      AY398348
      UniProtKB/TrEMBL
      Q6TH08
      Related
      ENSDARP00000073136.4, ENSDART00000078675.6
      Conserved Domains (1) summary
      pfam07200
      Location:225366
      Mod_r; Modifier of rudimentary (Mod(r)) protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      16463079..16480213
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394468.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      107538..125637
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)