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    fam76b family with sequence similarity 76 member B [ Danio rerio (zebrafish) ]

    Gene ID: 335015, updated on 9-Dec-2024

    Summary

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    Official Symbol
    fam76bprovided by ZNC
    Official Full Name
    family with sequence similarity 76 member Bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-6955
    See related
    Ensembl:ENSDARG00000012432 AllianceGenome:ZFIN:ZDB-GENE-030131-6955
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fa11h02; zgc:73333; wu:fa11h02
    Summary
    Predicted to be active in nuclear speck. Orthologous to human FAM76B (family with sequence similarity 76 member B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See fam76b in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (23585215..23596317, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (23081414..23092546, complement)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene acyl-CoA synthetase long chain family member 4b Neighboring gene CWC15 spliceosome associated protein homolog Neighboring gene K(lysine) acetyltransferase 5a Neighboring gene myotubularin related protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Expression and functional analysis of fam76b in zebrafish. Zhu J, et al. Fish Shellfish Immunol, 2023 Nov. PMID 37838209
    2. RNA-Seq analysis in mutant zebrafish reveals role of U1C protein in alternative splicing regulation. Rösel TD, et al. EMBO J, 2011 May 18. PMID 21468032, Free PMC Article
    3. New classes of mind bomb-interacting proteins identified from yeast two-hybrid screens. Tseng LC, et al. PLoS One, 2014. PMID 24714733, Free PMC Article
    4. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    is_active_in nuclear speck IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nuclear speck ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM76B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199932.1 → NP_956226.1  protein FAM76B

      See identical proteins and their annotated locations for NP_956226.1

      Status: PROVISIONAL

      Source sequence(s)
      BC059652
      UniProtKB/Swiss-Prot
      Q6PBM7
      Related
      ENSDARP00000026447.7, ENSDART00000024815.8
      Conserved Domains (1) summary
      pfam16046
      Location:6 → 317
      FAM76; FAM76 protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      23585215..23596317 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009301288.4 → XP_009299563.1  protein FAM76B isoform X1

      UniProtKB/TrEMBL
      A0A8M3B2A7
      Conserved Domains (1) summary
      pfam16046
      Location:6 → 316
      FAM76; FAM76 protein
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6PBM7.1 GenPept UniProtKB/Swiss-Prot:Q6PBM7

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