ppp2r2ca protein phosphatase 2, regulatory subunit B, gamma a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ppp2r2caprovided by ZNC
Official Full Name: protein phosphatase 2, regulatory subunit B, gamma aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-051120-168
See related: Ensembl:ENSDARG00000056797 AllianceGenome:ZFIN:ZDB-GENE-051120-168
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: ppp2r2c; zgc:123166
Summary: Predicted to enable protein phosphatase regulator activity. Predicted to be part of protein phosphatase type 2A complex. Predicted to be active in cytosol. Orthologous to human PPP2R2C (protein phosphatase 2 regulatory subunit Bgamma). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 1

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (14283692..14309997)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (13597179..13620524)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables protein phosphatase regulator activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein phosphatase regulator activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
part_of protein phosphatase type 2A complex	IBA Inferred from Biological aspect of Ancestor more info
part_of protein phosphatase type 2A complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: protein phosphatase 2, regulatory subunit B, gamma a

NP_001032471.1

EC 3.1.3.16

XP_068079050.1

EC 3.1.3.16

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001037394.1 → NP_001032471.1 protein phosphatase 2, regulatory subunit B, gamma a

See identical proteins and their annotated locations for NP_001032471.1

Status: PROVISIONAL

Source sequence(s)

BC109406

UniProtKB/TrEMBL

Q32LW2

Related

ENSDARP00000026825.9, ENSDART00000017679.10

Conserved Domains (3) summary

COG5170
Location:19 → 439

CDC55; Serine/threonine protein phosphatase 2A, regulatory subunit [Signal transduction mechanisms]

sd00039
Location:25 → 76

7WD40; WD40 repeat [structural motif]

cl02567
Location:23 → 367

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...