katna1 katanin p60 (ATPase containing) subunit A 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: katna1provided by ZNC
Official Full Name: katanin p60 (ATPase containing) subunit A 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-050522-514
See related: Ensembl:ENSDARG00000021827 AllianceGenome:ZFIN:ZDB-GENE-050522-514
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:110580; si:dkey-15j16.1
Summary: Predicted to enable ATP hydrolysis activity. Acts upstream of or within axon extension and cytoplasmic microtubule organization. Predicted to be located in cytoplasm; midbody; and mitotic spindle pole. Predicted to be active in microtubule cytoskeleton. Orthologous to human KATNA1 (katanin catalytic subunit A1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 20

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	20	NC_007131.7 (23860858..23876294, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	20	NC_007131.6 (23961964..23977201, complement)

Chromosome 20 - NC_007131.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

STS.G950 (e-PCR)
- UniSTS:205694

fc24d07.y1 (e-PCR)
- UniSTS:193196

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IBA Inferred from Biological aspect of Ancestor more info
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables isomerase activity	IEA Inferred from Electronic Annotation more info
enables microtubule binding	IEA Inferred from Electronic Annotation more info
enables microtubule severing ATPase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in anatomical structure morphogenesis	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within axon extension	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within axon extension	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within cell division	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cytoplasmic microtubule organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in microtubule severing	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within microtubule severing	IEA Inferred from Electronic Annotation more info
involved_in microtubule severing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in centrosome	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in microtubule	IEA Inferred from Electronic Annotation more info
is_active_in microtubule cytoskeleton	IBA Inferred from Biological aspect of Ancestor more info
located_in midbody	ISS Inferred from Sequence or Structural Similarity more info
located_in mitotic spindle pole	ISS Inferred from Sequence or Structural Similarity more info
located_in spindle pole	IEA Inferred from Electronic Annotation more info
located_in spindle pole	ISS Inferred from Sequence or Structural Similarity more info

General protein information

Go to the top of the page Help

Preferred Names: katanin p60 ATPase-containing subunit A1

NP_001018440.1

EC 5.6.1.1

XP_021324094.1

EC 5.6.1.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001020604.1 → NP_001018440.1 katanin p60 ATPase-containing subunit A1

See identical proteins and their annotated locations for NP_001018440.1

Status: PROVISIONAL

Source sequence(s)

BC095321

UniProtKB/Swiss-Prot

Q5RII9

UniProtKB/TrEMBL

A0A8M9PHA7

Related

ENSDARP00000043315.5, ENSDART00000043316.7

Conserved Domains (1) summary

COG0464
Location:184 → 478

SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007131.7 Reference GRCz11 Primary Assembly

Range

23860858..23876294 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021468419.2 → XP_021324094.1 katanin p60 ATPase-containing subunit A1 isoform X1

UniProtKB/Swiss-Prot

Q5RII9

UniProtKB/TrEMBL

A0A8M9PHA7

Conserved Domains (1) summary

COG0464
Location:184 → 478

SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]