glrx glutaredoxin (thioltransferase) [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: glrxprovided by ZNC
Official Full Name: glutaredoxin (thioltransferase)provided by ZNC
Primary source: ZFIN:ZDB-GENE-041010-11
See related: Ensembl:ENSDARG00000028106 AllianceGenome:ZFIN:ZDB-GENE-041010-11
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: grx; fc38f02; wu:fc38f02; zgc:103707
Summary: Predicted to enable glutathione disulfide oxidoreductase activity. Orthologous to human GLRX (glutaredoxin). [provided by Alliance of Genome Resources, Dec 2024]
Annotation information: Annotation category: partial on reference assembly
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 21

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	21	NC_007132.7 (11778828..11782089)
105	previous assembly	GRCz10 (GCF_000002035.5)	21	NC_007132.6 (11686200..11689461)

Chromosome 21 - NC_007132.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fd11h02.x1 (e-PCR)
- UniSTS:195147

fc38f02.x1 (e-PCR)
- UniSTS:188095

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables glutathione disulfide oxidoreductase activity	IBA Inferred from Biological aspect of Ancestor more info
enables glutathione-homocystine transhydrogenase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: glutaredoxin-1

NP_001005942.1

EC 1.8.4.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001005942.1 → NP_001005942.1 glutaredoxin-1

See identical proteins and their annotated locations for NP_001005942.1

Status: PROVISIONAL

Source sequence(s)

BC083468

UniProtKB/TrEMBL

Q5XJ42

Related

ENSDARP00000037864.7, ENSDART00000031786.8

Conserved Domains (1) summary

cd03419
Location:13 → 97

GRX_GRXh_1_2_like; Glutaredoxin (GRX) family, GRX human class 1 and 2 (h_1_2)-like subfamily; composed of proteins similar to human GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, ...