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    elmod2 ELMO/CED-12 domain containing 2 [ Danio rerio (zebrafish) ]

    Gene ID: 553267, updated on 9-Dec-2024

    Summary

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    Official Symbol
    elmod2provided by ZNC
    Official Full Name
    ELMO/CED-12 domain containing 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060824-2
    See related
    Ensembl:ENSDARG00000101669 AllianceGenome:ZFIN:ZDB-GENE-060824-2
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable GTPase activator activity. Predicted to be located in membrane. Orthologous to human ELMOD2 (ELMO domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See elmod2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (53391345..53407463, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (52756607..52772743, complement)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene TBC1 domain family, member 9 (with GRAM domain) Neighboring gene uncoupling protein 1 Neighboring gene uncharacterized LOC108190370 Neighboring gene zgc:66455

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Adaptive evolution of the uncoupling protein 1 gene contributed to the acquisition of novel nonshivering thermogenesis in ancestral eutherian mammals. Saito S, et al. Gene, 2008 Jan 31. PMID 18023297
    2. Uncoupling protein 1 in fish uncovers an ancient evolutionary history of mammalian nonshivering thermogenesis. Jastroch M, et al. Physiol Genomics, 2005 Jul 14. PMID 15886331
    3. Exploring uncoupling proteins and antioxidant mechanisms under acute cold exposure in brains of fish. Tseng YC, et al. PLoS One, 2011 Mar 25. PMID 21464954, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ELMO domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001204132.1 → NP_001191061.1  ELMO domain-containing protein 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AL935166
      UniProtKB/TrEMBL
      A0A8M1P1T7, A0A8M3AKQ9
      Related
      ENSDARP00000132763.1, ENSDART00000172322.2
      Conserved Domains (1) summary
      pfam04727
      Location:113 → 267
      ELMO_CED12; ELMO/CED-12 family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      53391345..53407463 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009294631.3 → XP_009292906.1  ELMO domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8M3AKQ9, A0A8M3AT43
      Conserved Domains (1) summary
      pfam04727
      Location:143 → 297
      ELMO_CED12; ELMO/CED-12 family
    Nucleotide Protein Strain
    Heading Accession and Version

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