amd1 adenosylmethionine decarboxylase 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: amd1provided by ZNC
Official Full Name: adenosylmethionine decarboxylase 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-760
See related: Ensembl:ENSDARG00000043856 AllianceGenome:ZFIN:ZDB-GENE-040426-760
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fb26e03; zgc:55614; wu:fb26e03; si:ch211-257g8.2
Summary: Predicted to enable adenosylmethionine decarboxylase activity. Predicted to be involved in spermidine biosynthetic process and spermine biosynthetic process. Predicted to act upstream of or within polyamine biosynthetic process. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human AMD1 (adenosylmethionine decarboxylase 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	20	NC_007131.7 (2950005..2978968)
105	previous assembly	GRCz10 (GCF_000002035.5)	20	NC_007131.6 (2937165..2966128)

Chromosome 20 - NC_007131.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

fb26e03 (e-PCR)
- UniSTS:189000

fj23h11.y1 (e-PCR)
- UniSTS:198841

fi85e02.y1 (e-PCR)
- UniSTS:198108

AI444373 (e-PCR)
- UniSTS:206567

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables adenosylmethionine decarboxylase activity	IBA Inferred from Biological aspect of Ancestor more info
enables adenosylmethionine decarboxylase activity	IEA Inferred from Electronic Annotation more info
enables carboxy-lyase activity	IEA Inferred from Electronic Annotation more info
enables lyase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within polyamine biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in spermidine biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within spermidine biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in spermine biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within spermine biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: S-adenosylmethionine decarboxylase proenzyme

NP_001155073.1

EC 4.1.1.50

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.