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    sec22a SEC22 homolog A, vesicle trafficking protein [ Danio rerio (zebrafish) ]

    Gene ID: 324832, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sec22aprovided by ZNC
    Official Full Name
    SEC22 homolog A, vesicle trafficking proteinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-3553
    See related
    Ensembl:ENSDARG00000078328 AllianceGenome:ZFIN:ZDB-GENE-030131-3553
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc44f07; sec22l2; zgc:56686; wu:fc44f07
    Summary
    Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in endoplasmic reticulum membrane. Orthologous to human SEC22A (SEC22 homolog A, vesicle trafficking protein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See sec22a in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (37850425..37860493)
    105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (38040666..38050698)

    Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Ba Neighboring gene uncharacterized LOC137496490 Neighboring gene uncharacterized LOC137496491 Neighboring gene protein disulfide isomerase family A, member 5 Neighboring gene adenylate cyclase 5 Neighboring gene 3-hydroxyacyl-CoA dehydratase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Functional characterization of Atlantic salmon (Salmo salar L.) PepT2 transporters. Vacca F, et al. J Physiol, 2022 May. PMID 35413133, Free PMC Article
    2. B cells in teleost fish act as pivotal initiating APCs in priming adaptive immunity: an evolutionary perspective on the origin of the B-1 cell subset and B7 molecules. Zhu LY, et al. J Immunol, 2014 Mar 15. PMID 24532580
    3. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within endoplasmic reticulum to Golgi vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    vesicle-trafficking protein SEC22a
    Names
    SEC22 vesicle trafficking protein homolog A
    SEC22 vesicle trafficking protein-like 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199698.1 → NP_955992.1  vesicle-trafficking protein SEC22a

      See identical proteins and their annotated locations for NP_955992.1

      Status: PROVISIONAL

      Source sequence(s)
      BC049530
      UniProtKB/TrEMBL
      Q7ZW89
      Related
      ENSDARP00000076602.5, ENSDART00000082165.7
      Conserved Domains (2) summary
      COG5143
      Location:8 → 146
      SNC1; Synaptobrevin/VAMP-like protein [Intracellular trafficking and secretion]
      pfam13774
      Location:38 → 106
      Longin; Regulated-SNARE-like domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007120.7 Reference GRCz11 Primary Assembly

      Range
      37850425..37860493
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021478609.2 → XP_021334284.1  vesicle-trafficking protein SEC22a isoform X1

      UniProtKB/TrEMBL
      A0A8M9QAL1, F1QBW3
      Conserved Domains (1) summary
      pfam13774
      Location:38 → 114
      Longin; Regulated-SNARE-like domain
    Nucleotide Protein
    Heading Accession and Version

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