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    elapor2b endosome-lysosome associated apoptosis and autophagy regulator family member 2b [ Danio rerio (zebrafish) ]

    Gene ID: 566596, updated on 9-Dec-2024

    Summary

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    Official Symbol
    elapor2bprovided by ZNC
    Official Full Name
    endosome-lysosome associated apoptosis and autophagy regulator family member 2bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-3893
    See related
    Ensembl:ENSDARG00000004386 AllianceGenome:ZFIN:ZDB-GENE-030131-3893
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc57c04; wu:fc57c04; si:ch73-161g10.2; si:dkey-153k10.9
    Summary
    Predicted to be involved in positive regulation of BMP signaling pathway. Predicted to be located in plasma membrane. Predicted to be active in membrane. Orthologous to human ELAPOR2 (endosome-lysosome associated apoptosis and autophagy regulator family member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See elapor2b in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (9669673..9690419)
    105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (9668704..9689503)

    Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137490074 Neighboring gene si:dkey-153k10.7 Neighboring gene cyclin D binding myb-like transcription factor 1 Neighboring gene tetraspanin 9b Neighboring gene microtubule associated monooxygenase, calponin and LIM domain containing 3b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. A live zebrafish-based screening system for human nuclear receptor ligand and cofactor discovery. Tiefenbach J, et al. PLoS One, 2010 Mar 22. PMID 20339547, Free PMC Article
    2. Eumetazoan cryptochrome phylogeny and evolution. Haug MF, et al. Genome Biol Evol, 2015 Jan 18. PMID 25601102, Free PMC Article
    3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in positive regulation of BMP signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    endosome/lysosome-associated apoptosis and autophagy regulator family member 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001045110.1 → NP_001038575.1  endosome/lysosome-associated apoptosis and autophagy regulator family member 2 precursor

      Status: PROVISIONAL

      Source sequence(s)
      BX901962
      UniProtKB/TrEMBL
      A0A8M1NA23, Q5RGE8
      Related
      ENSDARP00000025192.8, ENSDART00000004604.9
      Conserved Domains (2) summary
      pfam07699
      Location:256 → 295
      GCC2_GCC3; GCC2 and GCC3
      cl22855
      Location:361 → 396
      TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007115.7 Reference GRCz11 Primary Assembly

      Range
      9669673..9690419
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005164587.5 → XP_005164644.1  endosome/lysosome-associated apoptosis and autophagy regulator family member 2 isoform X1

      UniProtKB/TrEMBL
      A0A8M2BBU3
      Conserved Domains (2) summary
      pfam07699
      Location:256 → 295
      GCC2_GCC3; GCC2 and GCC3
      cl22855
      Location:361 → 396
      TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394550.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      225547..246246
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395230.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      93679..114381
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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