gins2 GINS complex subunit 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: gins2provided by ZNC
Official Full Name: GINS complex subunit 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-050419-19
See related: Ensembl:ENSDARG00000002304 AllianceGenome:ZFIN:ZDB-GENE-050419-19
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:112262; si:dkey-265o13.3
Summary: Predicted to be involved in double-strand break repair via break-induced replication. Predicted to act upstream of or within DNA replication. Predicted to be located in nucleus. Predicted to be part of GINS complex. Is expressed in ciliary marginal zone and optic tectum. Orthologous to human GINS2 (GINS complex subunit 2). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 18

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	18	NC_007129.7 (30481030..30499456, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	18	NC_007129.6 (30502776..30521202, complement)

Chromosome 18 - NC_007129.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

AI477029 (e-PCR)
- UniSTS:206534

fb54g02.x1 (e-PCR)
- UniSTS:190711

Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA replication	IEA Inferred from Electronic Annotation more info
involved_in DNA-templated DNA replication	IEA Inferred from Electronic Annotation more info
involved_in double-strand break repair via break-induced replication	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of GINS complex	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: DNA replication complex GINS protein PSF2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001024439.1 → NP_001019610.1 DNA replication complex GINS protein PSF2

See identical proteins and their annotated locations for NP_001019610.1

Status: PROVISIONAL

Source sequence(s)

BC095711

UniProtKB/TrEMBL

A0A8M1N6W9, Q4VBJ6

Related

ENSDARP00000035433.6, ENSDART00000033746.7

Conserved Domains (2) summary

cd11712
Location:55 → 174

GINS_A_psf2; Alpha-helical domain of GINS complex protein Psf2 (partner of Sld5 2)

cd21694
Location:2 → 63

GINS_B_Psf2; beta-strand (B) domain of GINS complex protein Psf2