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    rab1bb RAB1B, member RAS oncogene family b [ Danio rerio (zebrafish) ]

    Gene ID: 415219, updated on 4-Jan-2025

    Summary

    Official Symbol
    rab1bbprovided by ZNC
    Official Full Name
    RAB1B, member RAS oncogene family bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040625-133
    See related
    Ensembl:ENSDARG00000056479 AllianceGenome:ZFIN:ZDB-GENE-040625-133
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:86773; wu:fc83b07
    Summary
    Predicted to enable GTPase activity. Predicted to be involved in autophagosome assembly and intracellular protein transport. Predicted to be active in endomembrane system. Is expressed in central nervous system. Orthologous to several human genes including RAB1B (RAB1B, member RAS oncogene family). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
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    Genomic context

    See rab1bb in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (26926635..26933708)
    105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (26964922..26971995)

    Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 89 member B Neighboring gene EH domain binding protein 1-like 1b Neighboring gene endothelial zinc finger protein induced by tumor necrosis factor alpha-like Neighboring gene FERM domain containing 8

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC113919

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in autophagosome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    RAB1B, member RAS oncogene family b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002129.2NP_001002129.2  RAB1B, member RAS oncogene family b

      See identical proteins and their annotated locations for NP_001002129.2

      Status: VALIDATED

      Source sequence(s)
      CR450793, EH444733, EH525664
      UniProtKB/TrEMBL
      A0A8M1MZW9, Q4V984
      Related
      ENSDARP00000073437.4, ENSDART00000078980.6
      Conserved Domains (2) summary
      smart00175
      Location:9172
      RAB; Rab subfamily of small GTPases
      cd01869
      Location:7172
      Rab1_Ypt1; Rab GTPase family 1 includes the yeast homolog Ypt1

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007121.7 Reference GRCz11 Primary Assembly

      Range
      26926635..26933708
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394787.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      154262..161354
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)