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    rnf145b ring finger protein 145b [ Danio rerio (zebrafish) ]

    Gene ID: 327056, updated on 9-Dec-2024

    Summary

    Official Symbol
    rnf145bprovided by ZNC
    Official Full Name
    ring finger protein 145bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-5264
    See related
    Ensembl:ENSDARG00000032373 AllianceGenome:ZFIN:ZDB-GENE-030131-5264
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    rnf145; fa20f10; zgc:56435; wu:fa20f10
    Summary
    Predicted to enable ubiquitin protein ligase activity. Acts upstream of or within myeloid cell development. Predicted to be located in membrane. Predicted to be active in endomembrane system. Orthologous to human RNF145 (ring finger protein 145). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See rnf145b in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (34001712..34032650, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (33967222..33998160, complement)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101884235 Neighboring gene EBF transcription factor 1b Neighboring gene mitogen-activated protein kinase kinase kinase kinase 6 Neighboring gene zgc:110222

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in ERAD pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within hemopoiesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within myeloid cell development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    RING finger protein 145
    NP_956057.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199763.1NP_956057.1  RING finger protein 145

      See identical proteins and their annotated locations for NP_956057.1

      Status: PROVISIONAL

      Source sequence(s)
      BC049437
      UniProtKB/Swiss-Prot
      Q7ZWF4
      Related
      ENSDARP00000047514.6, ENSDART00000047515.7
      Conserved Domains (2) summary
      pfam13639
      Location:535575
      zf-RING_2; Ring finger domain
      pfam13705
      Location:8506
      TRC8_N; TRC8 N-terminal domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      34001712..34032650 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)