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    stom stomatin [ Danio rerio (zebrafish) ]

    Gene ID: 81534, updated on 9-Dec-2024

    Summary

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    Official Symbol
    stomprovided by ZNC
    Official Full Name
    stomatinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-980526-486
    See related
    Ensembl:ENSDARG00000003835 AllianceGenome:ZFIN:ZDB-GENE-980526-486
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    epb72; band72; band7.2; zgc:110814
    Summary
    Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human STOM (stomatin). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See stom in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (17542473..17570220)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (17505805..17533584)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene general transcription factor IIIC, polypeptide 4 Neighboring gene BarH-like homeobox 1b Neighboring gene gelsolin a Neighboring gene retinoid X receptor, alpha a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Vertebrate genome evolution and the zebrafish gene map. Postlethwait JH, et al. Nat Genet, 1998 Apr. PMID 9537416
    2. Gene duplication, conservation, and divergence of activating transcription factor 5 gene in zebrafish. Zhu H, et al. J Exp Zool B Mol Dev Evol, 2022 Jul. PMID 35226401
    3. A genetic linkage map for zebrafish: comparative analysis and localization of genes and expressed sequences. Gates MA, et al. Genome Res, 1999 Apr. PMID 10207156
    4. Many genes in fish have species-specific asymmetric rates of molecular evolution. Steinke D, et al. BMC Genomics, 2006 Feb 8. PMID 16466575, Free PMC Article
    5. A Toolbox for Efficient Proximity-Dependent Biotinylation in Zebrafish Embryos. Rosenthal SM, et al. Mol Cell Proteomics, 2021. PMID 34332124, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    stomatin
    Names
    erythrocyte protein band 7.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001320073.1 → NP_001307002.1  stomatin isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      CR762400
      UniProtKB/TrEMBL
      A0A8M1P7K2, F1QCQ7
      Related
      ENSDARP00000120230.1, ENSDART00000141326.2
      Conserved Domains (2) summary
      smart00244
      Location:64 → 216
      PHB; prohibitin homologues
      cd03403
      Location:85 → 286
      SPFH_stomatin; Stomatin, a subgroup of the stomatin-like proteins (slipins) family; belonging to the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

    2. NM_131758.2 → NP_571833.1  stomatin isoform 2

      See identical proteins and their annotated locations for NP_571833.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. It encodes isoform 2, which is shorter than isoform 1.
      Source sequence(s)
      CR762400
      UniProtKB/TrEMBL
      A0A8N7UZM9, O93423
      Related
      ENSDARP00000010282.4, ENSDART00000005750.6
      Conserved Domains (2) summary
      smart00244
      Location:54 → 206
      PHB; prohibitin homologues
      cd03403
      Location:75 → 276
      SPFH_stomatin; Stomatin, a subgroup of the stomatin-like proteins (slipins) family; belonging to the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      17542473..17570220
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017352833.3 → XP_017208322.1  stomatin isoform X1

      UniProtKB/TrEMBL
      A0A0R4IGK4, A0A8M6Z3Q4
      Related
      ENSDARP00000133615.1, ENSDART00000163238.3

    2. XM_017352834.3 → XP_017208323.1  stomatin isoform X2

      UniProtKB/TrEMBL
      A0A2R8RTR5, A0A8M6YUJ4
      Related
      ENSDARP00000152629.1, ENSDART00000191700.1

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395085.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      262258..289474
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395347.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      32544..60291
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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