eif4e1b eukaryotic translation initiation factor 4E family member 1B [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: eif4e1bprovided by ZNC
Official Full Name: eukaryotic translation initiation factor 4E family member 1Bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-980526-127
See related: Ensembl:ENSDARG00000014565 AllianceGenome:ZFIN:ZDB-GENE-980526-127
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: Z4ES; eif4e; zeIF4E; eIF4E-1B
Summary: Predicted to enable translation initiation factor activity. Predicted to be involved in regulation of translation and translational initiation. Predicted to be located in cytoplasm and nuclear speck. Predicted to be part of eukaryotic translation initiation factor 4F complex. Is expressed in several structures, including blastomere; hematopoietic cell; oocyte; optic vesicle; and segmental plate. Orthologous to human EIF4E1B (eukaryotic translation initiation factor 4E family member 1B). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 5

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (67787965..67799648, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (67110245..67121937, complement)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

eIF4E1b is a non-canonical eIF4E protecting maternal dormant mRNAs.
Title: eIF4E1b is a non-canonical eIF4E protecting maternal dormant mRNAs.
eIF4E-1A and eIF4E-1B are differentially expressed and functionally divergent
Title: Two zebrafish eIF4E family members are differentially expressed and functionally divergent.

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
NOT enables RNA 7-methylguanosine cap binding	IDA Inferred from Direct Assay more info	PubMed
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables translation initiation factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables translation initiation factor activity	IEA Inferred from Electronic Annotation more info
enables translation initiation factor activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in regulation of translation	ISS Inferred from Sequence or Structural Similarity more info
involved_in translational initiation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within translational initiation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
part_of eukaryotic translation initiation factor 4F complex	IBA Inferred from Biological aspect of Ancestor more info
part_of eukaryotic translation initiation factor 4F complex	ISS Inferred from Sequence or Structural Similarity more info
located_in nuclear speck	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: eukaryotic translation initiation factor 4E-1B

Names: eukaryotic translation initiation factor 4e 1b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.