ednrba endothelin receptor Ba [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ednrbaprovided by ZNC
Official Full Name: endothelin receptor Baprovided by ZNC
Primary source: ZFIN:ZDB-GENE-980526-16
See related: Ensembl:ENSDARG00000089334 AllianceGenome:ZFIN:ZDB-GENE-980526-16
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: ednrb1; ednrb1a
Summary: Predicted to enable endothelin receptor activity. Acts upstream of or within iridophore differentiation and regulation of developmental pigmentation. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in gill; head; iridophore; pigment cell; and trunk. Human ortholog(s) of this gene implicated in ABCD syndrome; Hirschsprung's disease; Waardenburg syndrome (multiple); asthma; and pulmonary hypertension. Orthologous to human EDNRB (endothelin receptor type B). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 1

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (28603768..28629624, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (27820834..27826119, complement)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables endothelin receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables endothelin receptor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in developmental pigmentation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within developmental pigmentation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in endothelin receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within enteric nervous system development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within iridophore differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of blood pressure	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of developmental pigmentation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info
involved_in vasoconstriction	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within vasoconstriction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: endothelin receptor Ba

Names: endothelin receptor B; endothelin receptor B1a; ros; rose; rse

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.