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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_131243.1 → NP_571318.1 complement C3a.2 precursor
See identical proteins and their annotated locations for NP_571318.1
Status: PROVISIONAL
- Source sequence(s)
-
AB235997
- UniProtKB/TrEMBL
-
Q3MU74
- Related
- ENSDARP00000108724.3, ENSDART00000127714.5
- Conserved Domains (9) summary
-
- cd00017
Location:674 → 729
- ANATO; Anaphylatoxin homologous domain; C3a, C4a and C5a anaphylatoxins are protein fragments generated enzymatically in serum during activation of complement molecules C3, C4, and C5. They induce smooth muscle contraction. These fragments are homologous to ...
- cd02896
Location:987 → 1272
- complement_C3_C4_C5; Proteins similar to C3, C4 and C5 of vertebrate complement. The vertebrate complement system, comprised of a large number of distinct plasma proteins, is an effector of both the acquired and innate immune systems. The point of convergence of the ...
- cd03583
Location:1502 → 1649
- NTR_complement_C3; NTR/C345C domain, complement C3 subfamily; The NTR domain found in complement C3 is also known as the C345C domain because it occurs at the C-terminus of complement C3, C4 and C5. Complement C3 plays a pivotal role in the activation of the complement ...
- pfam00207
Location:768 → 861
- A2M; Alpha-2-macroglobulin family
- pfam01835
Location:128 → 222
- A2M_N; MG2 domain
- pfam02488
Location:388 → 469
- EMA; Merozoite Antigen
- pfam07677
Location:1387 → 1482
- A2M_recep; A-macroglobulin receptor
- pfam07678
Location:1042 → 1272
- A2M_comp; A-macroglobulin complement component
- pfam07703
Location:463 → 599
- A2M_N_2; Alpha-2-macroglobulin family N-terminal region
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCz11 Primary Assembly
Genomic
-
NC_007112.7 Reference GRCz11 Primary Assembly
- Range
-
56229674..56266728
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)