U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Apobec2 apolipoprotein B mRNA editing enzyme catalytic subunit 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 301226, updated on 27-Dec-2024

    Summary

    Official Symbol
    Apobec2provided by RGD
    Official Full Name
    apolipoprotein B mRNA editing enzyme catalytic subunit 2provided by RGD
    Primary source
    RGD:1308727
    See related
    EnsemblRapid:ENSRNOG00000012303 AllianceGenome:RGD:1308727
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable cytidine deaminase activity and identical protein binding activity. Predicted to be involved in positive regulation of gene expression via chromosomal CpG island demethylation. Predicted to act upstream of or within cytidine to uridine editing and mRNA modification. Orthologous to human APOBEC2 (apolipoprotein B mRNA editing enzyme catalytic subunit 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 2212.8), Heart (RPKM 839.7) and 1 other tissue See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Apobec2 in Genome Data Viewer
    Location:
    9q12
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (20062561..20076074)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (12564955..12578461)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (14529218..14542731)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene unc-5 family C-terminal like Neighboring gene translocator protein 2 Neighboring gene O-acyl-ADP-ribose deacylase 1 Neighboring gene nuclear transcription factor Y subunit alpha Neighboring gene triggering receptor expressed on myeloid cells-like 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    C->U-editing enzyme APOBEC-2
    Names
    apolipoprotein B editing complex 2
    apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
    probable C->U-editing enzyme APOBEC-2
    NP_001100353.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106883.1NP_001100353.1  C->U-editing enzyme APOBEC-2

      See identical proteins and their annotated locations for NP_001100353.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473987
      UniProtKB/TrEMBL
      A6JIE5, B4F789, F7F9T5
      Related
      ENSRNOP00000016893.4, ENSRNOT00000016893.9
      Conserved Domains (1) summary
      pfam18778
      Location:46223
      NAD1; Novel AID APOBEC clade 1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      20062561..20076074
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)