Slc10a5 solute carrier family 10, member 5 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Slc10a5provided by RGD
Official Full Name: solute carrier family 10, member 5provided by RGD
Primary source: RGD:1306036
See related: EnsemblRapid:ENSRNOG00000067758 AllianceGenome:RGD:1306036
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable bile acid:sodium symporter activity. Predicted to be involved in bile acid and bile salt transport. Predicted to be located in membrane. Orthologous to human SLC10A5 (solute carrier family 10 member 5). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: 2q23

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (93364959..93366263)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (91457540..91458844)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (93669962..93671266)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Molecular cloning and characterization of SLC10A5 as an orphan carrier with yet non-identified substrates.
Title: The novel putative bile acid transporter SLC10A5 is highly expressed in liver and kidney.

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables bile acid:sodium symporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables symporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in bile acid and bile salt transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in sodium ion transport	IEA Inferred from Electronic Annotation more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: sodium/bile acid cotransporter 5

Names: Na(+)/bile acid cotransporter 5; solute carrier family 10 (sodium/bile acid cotransporter family), member 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.