U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ARAD1 Exostosin family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818076, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ARAD1
    Official Full Name
    Exostosin family protein
    Primary source
    TAIR:AT2G35100
    Locus tag
    AT2G35100
    See related
    Araport:AT2G35100
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABINAN DEFICIENT 1; ARABINOSYLTRANSFERASE; T4C15.23; T4C15_23
    Summary
    Putative glycosyltransferase, similar to other CAZy Family 47 proteins. The protein is predicted to be a type 2 membrane protein with a signal anchor and is predicted to be targeted to the secretory pathway and to have a single transmembrane helix near the N terminus; hence, the protein has the features expected for a type II membrane protein targeted to the Golgi vesicles. The gene was shown to be expressed in all tissues but particularly in vascular tissues of leaves and stems.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ARAD1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    3
    Sequence:
    Chromosome: 2; NC_003071.7 (14793567..14795701, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ATP binding / aminoacyl-tRNA ligase/ nucleotide binding protein Neighboring gene transmembrane protein, putative (DUF1640) Neighboring gene transcription activator Neighboring gene Single hybrid motif superfamily protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. ARABINAN DEFICIENT 1 is a putative arabinosyltransferase involved in biosynthesis of pectic arabinan in Arabidopsis. Harholt J, et al. Plant Physiol, 2006 Jan. PMID 16377743, Free PMC Article
    2. Cell wall pectic arabinans influence the mechanical properties of Arabidopsis thaliana inflorescence stems and their response to mechanical stress. Verhertbruggen Y, et al. Plant Cell Physiol, 2013 Aug. PMID 23695504
    3. ARAD proteins associated with pectic Arabinan biosynthesis form complexes when transiently overexpressed in planta. Harholt J, et al. Planta, 2012 Jul. PMID 22270560
    4. A reversible Renilla luciferase protein complementation assay for rapid identification of protein-protein interactions reveals the existence of an interaction network involved in xyloglucan biosynthesis in the plant Golgi apparatus. Lund CH, et al. J Exp Bot, 2015 Jan. PMID 25326916, Free PMC Article
    5. Separating Golgi Proteins from Cis to Trans Reveals Underlying Properties of Cisternal Localization. Parsons HT, et al. Plant Cell, 2019 Sep. PMID 31266899, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Arabinan deficient (arad) mutants display an altered response to mechanical stress in terms of inflorescence stem length reduction.
      Title: Cell wall pectic arabinans influence the mechanical properties of Arabidopsis thaliana inflorescence stems and their response to mechanical stress.
    2. These data show that ARAD2 is associated with arabinan biosynthesis, not redundant with ARAD1, and that the two glycosyltransferases may function in complexes held together by disulfide bridges in Arabidopsis thaliana..
      Title: ARAD proteins associated with pectic Arabinan biosynthesis form complexes when transiently overexpressed in planta.
    3. The gene is expressed in all tissues but particularly in vascular tissues of leaves and stems and is suggested to be an arabinan alpha-1,5-arabinosyltransferase.
      Title: ARABINAN DEFICIENT 1 is a putative arabinosyltransferase involved in biosynthesis of pectic arabinan in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_179910.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables glycosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within pectin biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in Golgi apparatus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in Golgi trans cisterna HDA PubMed 
    located_in Golgi trans cisterna IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endosome HDA PubMed 
    located_in trans-Golgi network HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    Exostosin family protein
    NP_850241.1
    • ARABINAN DEFICIENT 1 (ARAD1); FUNCTIONS IN: transferase activity, transferring glycosyl groups, catalytic activity; INVOLVED IN: pectin biosynthetic process; LOCATED IN: endomembrane system, membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Exostosin-like (InterPro:IPR004263); BEST Arabidopsis thaliana protein match is: Exostosin family protein (TAIR:AT5G44930.2); Has 1290 Blast hits to 1285 proteins in 106 species: Archae - 0; Bacteria - 8; Metazoa - 193; Fungi - 4; Plants - 1016; Viruses - 0; Other Eukaryotes - 69 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      14793567..14795701 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_179910.3 → NP_850241.1  Exostosin family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850241.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O82181, Q6DBG8
      UniProtKB/TrEMBL
      A0A178VSN1, A0A5S9X4B1
      Conserved Domains (1) summary
      pfam03016
      Location:56 → 368
      Exostosin; Exostosin family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6DBG8.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools