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    CTF18 P-loop containing nucleoside triphosphate hydrolases superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839431, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CTF18
    Official Full Name
    P-loop containing nucleoside triphosphate hydrolases superfamily protein
    Primary source
    TAIR:AT1G04730
    Locus tag
    AT1G04730
    See related
    Araport:AT1G04730
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    CHROMOSOME TRANSMISSION FIDELITY 18; T1G11.3; T1G11_3
    Summary
    Necessary for sister chromatid cohesion. Acts in synergy with ETG1.
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    Genomic context

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    See CTF18 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    22
    Sequence:
    Chromosome: 1; NC_003070.9 (1325099..1331169, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene peroxisomal 3-ketoacyl-CoA thiolase 4 Neighboring gene tRNA-Met Neighboring gene vesicle-associated membrane protein 721 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The MCM-binding protein ETG1 aids sister chromatid cohesion required for postreplicative homologous recombination repair. Takahashi N, et al. PLoS Genet, 2010 Jan 15. PMID 20090939, Free PMC Article
    2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

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    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within sister chromatid cohesion IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within sister chromatid cohesion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in replication fork TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    P-loop containing nucleoside triphosphate hydrolases superfamily protein
    NP_171966.2
    • CHROMOSOME TRANSMISSION FIDELITY 18 (CTF18); FUNCTIONS IN: nucleoside-triphosphatase activity, ATPase activity, nucleotide binding, ATP binding; INVOLVED IN: sister chromatid cohesion; LOCATED IN: replication fork; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959); BEST Arabidopsis thaliana protein match is: replication factor C1 (TAIR:AT5G22010.1); Has 4018 Blast hits to 4006 proteins in 709 species: Archae - 400; Bacteria - 666; Metazoa - 673; Fungi - 766; Plants - 379; Viruses - 21; Other Eukaryotes - 1113 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      1325099..1331169 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100352.3 → NP_171966.2  P-loop containing nucleoside triphosphate hydrolases superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_171966.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WFM0, A0A5S9SM12, F4I5S3
      Conserved Domains (1) summary
      PRK04195
      Location:337 → 650
      PRK04195; replication factor C large subunit; Provisional

    2. NM_001331495.1 → NP_001322020.1  P-loop containing nucleoside triphosphate hydrolases superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8ASP2

    3. NM_001331496.1 → NP_001322021.1  P-loop containing nucleoside triphosphate hydrolases superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8ASP2

    4. NM_001331497.1 → NP_001322022.1  P-loop containing nucleoside triphosphate hydrolases superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8ASP2
    Nucleotide Protein
    Heading Accession and Version

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