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    ARAC5 RAC-like GTP binding protein 5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843917, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ARAC5
    Official Full Name
    RAC-like GTP binding protein 5
    Primary source
    TAIR:AT1G75840
    Locus tag
    AT1G75840
    See related
    Araport:AT1G75840
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA GERANYLGERANYLATED PROTEIN 3; ATGP3; ATROP4; RAC-LIKE GTP BINDING PROTEIN; RAC-like GTP binding protein 5; RHO-LIKE GTP BINDING PROTEIN 4; ROP4
    Summary
    Belongs to the plant-specific ROP group of Rho GTPases; localized to the plasma membrane of tips of root hairs; involved in polar growth control.
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    Genomic context

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    See ARAC5 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    7
    Sequence:
    Chromosome: 1; NC_003070.9 (28475649..28477802)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene low-molecular-weight cysteine-rich 67 Neighboring gene VPS35 homolog B Neighboring gene DNA ligase Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The phosphomimetic mutation of an evolutionarily conserved serine residue affects the signaling properties of Rho of plants (ROPs). Fodor-Dunai C, et al. Plant J, 2011 May. PMID 21309864
    2. Structural evidence for a common intermediate in small G protein-GEF reactions. Thomas C, et al. Mol Cell, 2007 Jan 12. PMID 17218277
    3. Arabidopsis thaliana Rop GTPases are localized to tips of root hairs and control polar growth. Molendijk AJ, et al. EMBO J, 2001 Jun 1. PMID 11387211, Free PMC Article
    4. Localization of AtROP4 and AtROP6 and interaction with the guanine nucleotide dissociation inhibitor AtRhoGDI1 from Arabidopsis. Bischoff F, et al. Plant Mol Biol, 2000 Feb. PMID 10798620
    5. Cloning and characterization of rac-like cDNAs from Arabidopsis thaliana. Winge P, et al. Plant Mol Biol, 1997 Nov. PMID 9349271

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_106234.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTP binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables GTP binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables GTPase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within pollen tube growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in root hair elongation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in root hair initiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in small GTPase-mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in nucleolus HDA PubMed 
    located_in nucleus HDA PubMed 
    located_in phragmoplast HDA PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    RAC-like GTP binding protein 5
    NP_177712.1
    • RAC-like GTP binding protein 5 (ARAC5); CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Ras (InterPro:IPR013753), Small GTPase, Rho type (InterPro:IPR003578); BEST Arabidopsis thaliana protein match is: RHO-related protein from plants 2 (TAIR:AT1G20090.1); Has 24632 Blast hits to 24606 proteins in 682 species: Archae - 9; Bacteria - 69; Metazoa - 12688; Fungi - 3833; Plants - 2700; Viruses - 20; Other Eukaryotes - 5313 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      28475649..28477802
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_106234.3 → NP_177712.1  RAC-like GTP binding protein 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177712.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O48545, Q38937, Q9LQT0, Q9ZRD5
      UniProtKB/TrEMBL
      A0A178W747, A0A5S9WUP4, A0A7G2ESY8
      Conserved Domains (1) summary
      cd04133
      Location:6 → 178
      Rop_like; Rho-related protein from plants (Rop)-like
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q38937.1

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