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    ERF8 ethylene response factor 8 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841751, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ERF8
    Official Full Name
    ethylene response factor 8
    Primary source
    TAIR:AT1G53170
    Locus tag
    AT1G53170
    See related
    Araport:AT1G53170
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATERF-8; ATERF8; ERF TRANSCRIPTION FACTOR8; ETHYLENE RESPONSE ELEMENT BINDING FACTOR 4; ethylene response factor 8; F8L10.19
    Summary
    encodes a member of the ERF (ethylene response factor) subfamily B-1 of ERF/AP2 transcription factor family (ATERF-8). The protein contains one AP2 domain. There are 15 members in this subfamily including ATERF-3, ATERF-4, ATERF-7, and leafy petiole.
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    Genomic context

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    See ERF8 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (19821337..19822399, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Protein kinase superfamily protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene RING/U-box superfamily protein Neighboring gene TAF RNA polymerase I subunit A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis ETHYLENE RESPONSE FACTOR 8 (ERF8) has dual functions in ABA signaling and immunity. Cao FY, et al. BMC Plant Biol, 2018 Sep 27. PMID 30261844, Free PMC Article
    2. A regulatory cascade involving class II ETHYLENE RESPONSE FACTOR transcriptional repressors operates in the progression of leaf senescence. Koyama T, et al. Plant Physiol, 2013 Jun. PMID 23629833, Free PMC Article
    3. Repression domains of class II ERF transcriptional repressors share an essential motif for active repression. Ohta M, et al. Plant Cell, 2001 Aug. PMID 11487705, Free PMC Article
    4. The AP2/EREBP family of plant transcription factors. Riechmann JL, et al. Biol Chem, 1998 Jun. PMID 9687012
    5. An abscisic acid-responsive protein interaction network for sucrose non-fermenting related kinase1 in abiotic stress response. Carianopol CS, et al. Commun Biol, 2020 Mar 26. PMID 32218501, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Transcriptional repressor ERF8 has dual roles in abscisic acid signaling, pathogen defense and immunity.
      Title: Arabidopsis ETHYLENE RESPONSE FACTOR 8 (ERF8) has dual functions in ABA signaling and immunity.
    2. AtERF4 and AtERF8 regulated the expression of many genes involved in the progression of leaf senescence.
      Title: A regulatory cascade involving class II ETHYLENE RESPONSE FACTOR transcriptional repressors operates in the progression of leaf senescence.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_104196.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within ethylene-activated signaling pathway TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in intracellular anatomical structure TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in nucleus IC
    Inferred by Curator
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ethylene response factor 8
    NP_175725.1
    • ethylene response factor 8 (ERF8); CONTAINS InterPro DOMAIN/s: DNA-binding, integrase-type (InterPro:IPR016177), Pathogenesis-related transcriptional factor/ERF, DNA-binding (InterPro:IPR001471); BEST Arabidopsis thaliana protein match is: ethylene responsive element binding factor 4 (TAIR:AT3G15210.1); Has 5970 Blast hits to 5718 proteins in 254 species: Archae - 0; Bacteria - 2; Metazoa - 0; Fungi - 0; Plants - 5959; Viruses - 0; Other Eukaryotes - 9 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      19821337..19822399 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104196.3 → NP_175725.1  ethylene response factor 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_175725.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9MAI5
      UniProtKB/TrEMBL
      A0A178WCR7, A0A5S9WPJ6
      Conserved Domains (1) summary
      smart00380
      Location:30 → 86
      AP2; DNA-binding domain in plant proteins such as APETALA2 and EREBPs
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9MAI5.1

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