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    ddf2 Integrase-type DNA-binding superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842606, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ddf2
    Official Full Name
    Integrase-type DNA-binding superfamily protein
    Primary source
    TAIR:AT1G63030
    Locus tag
    AT1G63030
    See related
    Araport:AT1G63030
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    DWARF AND DELAYED FLOWERING 2; F16P17.20; F16P17_20
    Summary
    encodes a member of the DREB subfamily A-1 of ERF/AP2 transcription factor family (DDF2). The protein contains one AP2 domain. There are six members in this subfamily, including CBF1, CBF2, and CBF3. Overexpression of this gene results in the reduction of gibberellic acid biosynthesis. This gene is expressed in all tissues examined, but most abundantly expressed in rosette leaves and stems. Overexpression of DDF1, a putative paralog of this gene, also reduces gibberellic acid biosynthesis and makes the plants more tolerant to high-salinity levels.
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    Genomic context

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    See ddf2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (23367394..23368416, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene nuclear RNA polymerase D1A Neighboring gene ncRNA Neighboring gene miscRNA Neighboring gene MBOAT (membrane bound O-acyl transferase) family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular Evidence for Functional Divergence and Decay of a Transcription Factor Derived from Whole-Genome Duplication in Arabidopsis thaliana. Lehti-Shiu MD, et al. Plant Physiol, 2015 Aug. PMID 26103993, Free PMC Article
    2. dwarf and delayed-flowering 1, a novel Arabidopsis mutant deficient in gibberellin biosynthesis because of overexpression of a putative AP2 transcription factor. Magome H, et al. Plant J, 2004 Mar. PMID 14871311
    3. Identification and characterization of transcription factors regulating Arabidopsis HAK5. Hong JP, et al. Plant Cell Physiol, 2013 Sep. PMID 23825216
    4. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Riechmann JL, et al. Science, 2000 Dec 15. PMID 11118137
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data indicate that both transcription factors DWARF AND DELAYED FLOWERING1 (DDF1) and DDF2 are under selective constraint.
      Title: Molecular Evidence for Functional Divergence and Decay of a Transcription Factor Derived from Whole-Genome Duplication in Arabidopsis thaliana.
    2. Data indicate that the transcript levels of HAK5 and four transcriptin factor genes DDF2, JLO, bHLH121 and TFII_A were highly up-regulated in response to both -K and salt stress.
      Title: Identification and characterization of transcription factors regulating Arabidopsis HAK5.
    Submit: New GeneRIF Correction

    General gene information

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    NM_001084295.2
    NM_104981.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of gibberellin biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of timing of transition from vegetative to reproductive phase IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Integrase-type DNA-binding superfamily protein
    NP_001077764.1
    • DWARF AND DELAYED FLOWERING 2 (ddf2); CONTAINS InterPro DOMAIN/s: DNA-binding, integrase-type (InterPro:IPR016177), Pathogenesis-related transcriptional factor/ERF, DNA-binding (InterPro:IPR001471); BEST Arabidopsis thaliana protein match is: Integrase-type DNA-binding superfamily protein (TAIR:AT1G12610.1); Has 5240 Blast hits to 5238 proteins in 236 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 5235; Viruses - 0; Other Eukaryotes - 5 (source: NCBI BLink).
    NP_176491.1
    • DWARF AND DELAYED FLOWERING 2 (ddf2); CONTAINS InterPro DOMAIN/s: DNA-binding, integrase-type (InterPro:IPR016177), Pathogenesis-related transcriptional factor/ERF, DNA-binding (InterPro:IPR001471); BEST Arabidopsis thaliana protein match is: Integrase-type DNA-binding superfamily protein (TAIR:AT1G12610.1); Has 5240 Blast hits to 5238 proteins in 236 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 5235; Viruses - 0; Other Eukaryotes - 5 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      23367394..23368416 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001084295.2 → NP_001077764.1  Integrase-type DNA-binding superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077764.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q1ECJ2, Q680B6, Q6J9T4, Q9SGJ6
      UniProtKB/TrEMBL
      A0A5S9WT19, A0A654EKI6
      Conserved Domains (1) summary
      cd00018
      Location:28 → 88
      AP2; DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP (ethylene responsive element binding protein). In EREBPs the domain specifically binds to the 11bp GCC box of the ethylene response element (ERE), a promotor ...

    2. NM_104981.4 → NP_176491.1  Integrase-type DNA-binding superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176491.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q1ECJ2, Q680B6, Q6J9T4, Q9SGJ6
      UniProtKB/TrEMBL
      A0A5S9WT19, A0A654EKI6
      Conserved Domains (1) summary
      cd00018
      Location:28 → 88
      AP2; DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP (ethylene responsive element binding protein). In EREBPs the domain specifically binds to the 11bp GCC box of the ethylene response element (ERE), a promotor ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SGJ6.1

    Gene LinkOut

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