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    ATN cyclin family [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819697, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ATN
    Official Full Name
    cyclin family
    Primary source
    TAIR:AT3G05330
    Locus tag
    AT3G05330
    See related
    Araport:AT3G05330
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    A. THALIANA TAN1; ATTAN; T12H1.30; T12H1_30; TANGLED
    Summary
    Encodes a protein with moderate sequence similarity to the maize microtubule-binding protein TANGLED1. A single base-pair deletion (-A) at position Chr3:1519176 in Columbia relative to the Landsberg erecta and Achkarren-2 ecotype (see ESTs DR378436 and CB26450) introduces a frame-shift and premature termination codon. The protein encoded from the Columbia gene is truncated by 29 amino acids relative to the Landsberg erecta and Achkarren-2 encoded proteins. Involved in the identification of the division plane during mitosis amd cytokinesis
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    Genomic context

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    See ATN in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    4
    Sequence:
    Chromosome: 3; NC_003074.8 (1518857..1521909, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene MIRO-related GTP-ase 3 Neighboring gene O-fucosyltransferase family protein Neighboring gene Cyclin family protein Neighboring gene Chaperone DnaJ-domain superfamily protein Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene Metallopeptidase M24 family protein Neighboring gene receptor like protein 30

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Tangled localization at the cortical division site of plant cells occurs by several mechanisms. Rasmussen CG, et al. J Cell Sci, 2011 Jan 15. PMID 21172800
    2. Arabidopsis TANGLED identifies the division plane throughout mitosis and cytokinesis. Walker KL, et al. Curr Biol, 2007 Nov 6. PMID 17964159, Free PMC Article
    3. Division Plane Orientation Defects Revealed by a Synthetic Double Mutant Phenotype. Mir R, et al. Plant Physiol, 2018 Jan. PMID 29146775, Free PMC Article
    4. Two kinesins are involved in the spatial control of cytokinesis in Arabidopsis thaliana. Müller S, et al. Curr Biol, 2006 May 9. PMID 16682350
    5. RanGAP1 is a continuous marker of the Arabidopsis cell division plane. Xu XM, et al. Proc Natl Acad Sci U S A, 2008 Nov 25. PMID 19011093, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. tan1 air9 double mutants have a synthetic (or synergistic) phenotype consisting of defects in root growth, division plane orientation, and differentiation zone root cell file rotation, suggesting both mitotic and interphase microtubule functions. [TAN1]
      Title: Division Plane Orientation Defects Revealed by a Synthetic Double Mutant Phenotype.
    2. TAN is actively recruited to the cortical division site by distinct mechanisms before and after preprophase band disassembly.
      Title: Tangled localization at the cortical division site of plant cells occurs by several mechanisms.
    3. AT3G05330 AtTAN is implicated as a component of a cortical guidance cue that remains behind when the preprophase band (PPB) is disassembled and directs the expanding phragmoplast to the former PPB site during cytokinesis.
      Title: Arabidopsis TANGLED identifies the division plane throughout mitosis and cytokinesis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_111406.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within phragmoplast assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of phragmoplast microtubule organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    part_of microtubule associated complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in preprophase band IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cyclin family
    NP_187184.2
    • TANGLED (ATN); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: cytokinesis, initiation of separation, phragmoplast assembly; LOCATED IN: microtubule associated complex, preprophase band; EXPRESSED IN: cultured cell; Has 705 Blast hits to 473 proteins in 108 species: Archae - 0; Bacteria - 3; Metazoa - 504; Fungi - 31; Plants - 75; Viruses - 28; Other Eukaryotes - 64 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      1518857..1521909 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111406.5 → NP_187184.2  cyclin family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187184.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q197W8, Q84M91, Q9MA86
      UniProtKB/TrEMBL
      A0A178V6U9
      Conserved Domains (1) summary
      pfam03263
      Location:173 → 221
      Cucumo_2B; Cucumovirus protein 2B
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q84M91.1

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