U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    DEG7 DegP protease 7 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821268, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    DEG7
    Official Full Name
    DegP protease 7
    Primary source
    TAIR:AT3G03380
    Locus tag
    AT3G03380
    See related
    Araport:AT3G03380
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AT3G03390; DegP protease 7; DegP7; degradation of periplasmic proteins 7; T21P5.20; T21P5_20
    Summary
    Encodes a putative DegP protease.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See DEG7 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    24
    Sequence:
    Chromosome: 3; NC_003074.8 (799500..808540)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene F-box/RNI-like superfamily protein Neighboring gene uncharacterized protein Neighboring gene EF hand calcium-binding protein family Neighboring gene F-box associated ubiquitination effector family protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A new principle of oligomerization of plant DEG7 protease based on interactions of degenerated protease domains. Schuhmann H, et al. Biochem J, 2011 Apr 1. PMID 21247409, Free PMC Article
    2. The stromal chloroplast Deg7 protease participates in the repair of photosystem II after photoinhibition in Arabidopsis. Sun X, et al. Plant Physiol, 2010 Mar. PMID 20089771, Free PMC Article
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. DEG7 forms trimeric complexes, but in contrast with other known DegP/HtrA proteases, DEG7 shows a new principle of oligomerization, where trimerization is based on the interactions between degenerated protease domains.
      Title: A new principle of oligomerization of plant DEG7 protease based on interactions of degenerated protease domains.
    2. Deg7 is a chloroplast stroma protein associated with the thylakoid membranes and that it is important for maintaining PSII function.
      Title: The stromal chloroplast Deg7 protease participates in the repair of photosystem II after photoinhibition in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_001337469.1
    NM_111209.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables peptidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within photoinhibition IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    DegP protease 7
    NP_566204.2
    • DegP protease 7 (DegP7); CONTAINS InterPro DOMAIN/s: Serine/cysteine peptidase, trypsin-like (InterPro:IPR009003), Peptidase S1C, HrtA/DegP2/Q/S (InterPro:IPR001940), PDZ/DHR/GLGF (InterPro:IPR001478); BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT3G03370.1); Has 8327 Blast hits to 7895 proteins in 2064 species: Archae - 65; Bacteria - 6254; Metazoa - 235; Fungi - 503; Plants - 137; Viruses - 0; Other Eukaryotes - 1133 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      799500..808540
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111209.3 → NP_566204.2  DegP protease 7 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566204.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8RY22, Q9SRP2, Q9SRP3
      UniProtKB/TrEMBL
      A0A178VKJ3
      Conserved Domains (5) summary
      COG0265
      Location:39 → 372
      DegQ; Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]
      cd00987
      Location:280 → 366
      PDZ_serine_protease; PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind ...
      pfam12812
      Location:373 → 446
      PDZ_1; PDZ-like domain
      pfam13365
      Location:74 → 220
      Trypsin_2; Trypsin-like peptidase domain
      cl00117
      Location:971 → 1047
      PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

    2. NM_001337469.1 → NP_001326670.1  DegP protease 7 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VL82, A0A1I9LPZ9, A0A5S9X919, A0A654FE75
      Conserved Domains (4) summary
      COG0265
      Location:39 → 372
      DegQ; Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]
      TIGR02037
      Location:789 → 1019
      degP_htrA_DO; periplasmic serine protease, Do/DeqQ family
      pfam13365
      Location:611 → 765
      Trypsin_2; Trypsin-like peptidase domain
      cl00117
      Location:373 → 446
      PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8RY22.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools