U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    NIK2 NSP-interacting kinase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 822143, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    NIK2
    Official Full Name
    NSP-interacting kinase 2
    Primary source
    TAIR:AT3G25560
    Locus tag
    AT3G25560
    See related
    Araport:AT3G25560
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtNIK2; NSP-interacting kinase 2
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See NIK2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    12
    Sequence:
    Chromosome: 3; NC_003074.8 (9279513..9282906, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene TRAM, LAG1 and CLN8 (TLC) lipid-sensing domain containing protein Neighboring gene trigger factor Neighboring gene F-box family protein Neighboring gene ncRNA Neighboring gene Adenosylmethionine decarboxylase family protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The ribosomal protein L10/QM-like protein is a component of the NIK-mediated antiviral signaling. Rocha CS, et al. Virology, 2008 Oct 25. PMID 18789471
    2. An extracellular network of Arabidopsis leucine-rich repeat receptor kinases. Smakowska-Luzan E, et al. Nature, 2018 Jan 18. PMID 29320478, Free PMC Article
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_001203042.1
    NM_113453.3
    NM_202631.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    NSP-interacting kinase 2
    NP_001189971.1
    • NSP-interacting kinase 2 (NIK2); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: endomembrane system; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Leucine-rich repeat (InterPro:IPR001611), Leucine-rich repeat-containing N-terminal domain, type 2 (InterPro:IPR013210), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: NSP-interacting kinase 1 (TAIR:AT5G16000.1).
    NP_189183.2
    • NSP-interacting kinase 2 (NIK2); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: endomembrane system; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Leucine-rich repeat-containing N-terminal domain, type 2 (InterPro:IPR013210), Leucine-rich repeat (InterPro:IPR001611), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: NSP-interacting kinase 1 (TAIR:AT5G16000.1); Has 173817 Blast hits to 117543 proteins in 4488 species: Archae - 109; Bacteria - 15009; Metazoa - 43670; Fungi - 8369; Plants - 87261; Viruses - 427; Other Eukaryotes - 18972 (source: NCBI BLink).
    NP_974360.1
    • NSP-interacting kinase 2 (NIK2); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: endomembrane system; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Leucine-rich repeat-containing N-terminal domain, type 2 (InterPro:IPR013210), Leucine-rich repeat (InterPro:IPR001611), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: NSP-interacting kinase 1 (TAIR:AT5G16000.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      9279513..9282906 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113453.3 → NP_189183.2  NSP-interacting kinase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_189183.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8RY65, Q9LSU7
      UniProtKB/TrEMBL
      A0A178VEX6, A0A5S9XFT9
      Conserved Domains (3) summary
      PLN00113
      Location:42 → 199
      PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
      sd00033
      Location:107 → 130
      LRR_RI; leucine-rich repeat [structural motif]
      cl21453
      Location:318 → 584
      PKc_like; Protein Kinases, catalytic domain

    2. NM_001203042.1 → NP_001189971.1  NSP-interacting kinase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001189971.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9XFT9, F4JA15
      Conserved Domains (6) summary
      smart00219
      Location:319 → 581
      TyrKc; Tyrosine kinase, catalytic domain
      sd00033
      Location:107 → 130
      LRR_RI; leucine-rich repeat [structural motif]
      pfam08263
      Location:40 → 79
      LRRNT_2; Leucine rich repeat N-terminal domain
      pfam12799
      Location:153 → 190
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:130 → 189
      LRR_8; Leucine rich repeat
      cl21453
      Location:318 → 584
      PKc_like; Protein Kinases, catalytic domain

    3. NM_202631.2 → NP_974360.1  NSP-interacting kinase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974360.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9XFT9, F4JA17
      Conserved Domains (5) summary
      smart00219
      Location:320 → 582
      TyrKc; Tyrosine kinase, catalytic domain
      sd00033
      Location:107 → 130
      LRR_RI; leucine-rich repeat [structural motif]
      pfam08263
      Location:40 → 79
      LRRNT_2; Leucine rich repeat N-terminal domain
      pfam13855
      Location:130 → 190
      LRR_8; Leucine rich repeat
      cl21453
      Location:319 → 585
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8RY65.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.