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    Adaptin family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 826741, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Adaptin family protein
    Primary source
    TAIR:AT4G11380
    Locus tag
    AT4G11380
    See related
    Araport:AT4G11380
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    17
    Sequence:
    Chromosome: 4; NC_003075.7 (6919817..6925969)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene RING-H2 finger A1A Neighboring gene Serine/Threonine kinase catalytic domain protein Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene Cysteine/Histidine-rich C1 domain family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. AP1/2β-mediated exocytosis of tapetum-specific transporters is required for pollen development in Arabidopsis thaliana. Liu C, et al. Plant Cell, 2022 Sep 27. PMID 35766888, Free PMC Article
    2. The clathrin adaptor complex AP-2 mediates endocytosis of brassinosteroid insensitive1 in Arabidopsis. Di Rubbo S, et al. Plant Cell, 2013 Aug. PMID 23975899, Free PMC Article
    3. The non-JAZ TIFY protein TIFY8 from Arabidopsis thaliana is a transcriptional repressor. Cuéllar Pérez A, et al. PLoS One, 2014. PMID 24416306, Free PMC Article
    4. Identification and dynamics of Arabidopsis adaptor protein-2 complex and its involvement in floral organ development. Yamaoka S, et al. Plant Cell, 2013 Aug. PMID 23975897, Free PMC Article
    5. Novel Aquaporin Regulatory Mechanisms Revealed by Interactomics. Bellati J, et al. Mol Cell Proteomics, 2016 Nov. PMID 27609422, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001203772.1
    NM_117209.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables clathrin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of clathrin adaptor complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol HDA PubMed 
    NOT located_in cytosol RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in trans-Golgi network IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Adaptin family protein
    NP_001190701.1
    • Adaptin family protein; FUNCTIONS IN: protein transporter activity, clathrin binding, binding; INVOLVED IN: intracellular protein transport, vesicle-mediated transport, protein transport; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain (InterPro:IPR008152), Armadillo-like helical (InterPro:IPR011989), Clathrin/coatomer adaptor, adaptin-like, N-terminal (InterPro:IPR002553), Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain (InterPro:IPR013037), Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain (InterPro:IPR015151), Beta2-adaptin/TATA-box binding, C-terminal (InterPro:IPR012295), Armadillo-type fold (InterPro:IPR016024), Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain (InterPro:IPR009028), Adaptor protein complex, beta subunit (InterPro:IPR016342), Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain (InterPro:IPR013041); BEST Arabidopsis thaliana protein match is: Adaptin family protein (TAIR:AT4G23460.1).
    NP_192877.1
    • Adaptin family protein; FUNCTIONS IN: protein transporter activity, clathrin binding, binding; INVOLVED IN: intracellular protein transport, vesicle-mediated transport, protein transport; LOCATED IN: plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain (InterPro:IPR008152), Armadillo-like helical (InterPro:IPR011989), Clathrin/coatomer adaptor, adaptin-like, N-terminal (InterPro:IPR002553), Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain (InterPro:IPR013037), Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain (InterPro:IPR015151), Beta2-adaptin/TATA-box binding, C-terminal (InterPro:IPR012295), Armadillo-type fold (InterPro:IPR016024), Adaptor protein complex, beta subunit (InterPro:IPR016342), Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain (InterPro:IPR009028), Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain (InterPro:IPR013041); BEST Arabidopsis thaliana protein match is: Adaptin family protein (TAIR:AT4G23460.1); Has 3548 Blast hits to 3463 proteins in 290 species: Archae - 10; Bacteria - 21; Metazoa - 1495; Fungi - 876; Plants - 441; Viruses - 0; Other Eukaryotes - 705 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      6919817..6925969
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_117209.5 → NP_192877.1  Adaptin family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_192877.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M650, Q9SUS3
      UniProtKB/TrEMBL
      A0A178V7X9, A0A5S9XR99
      Conserved Domains (4) summary
      smart00809
      Location:673 → 772
      Alpha_adaptinC2; Adaptin C-terminal domain
      smart01020
      Location:782 → 893
      B2-adapt-app_C; Beta2-adaptin appendage, C-terminal sub-domain
      sd00044
      Location:56 → 77
      HEAT; HEAT repeat [structural motif]
      pfam01602
      Location:13 → 535
      Adaptin_N; Adaptin N terminal region

    2. NM_001203772.1 → NP_001190701.1  Adaptin family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190701.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9XR99, F4JNZ8
      Conserved Domains (4) summary
      smart00809
      Location:695 → 794
      Alpha_adaptinC2; Adaptin C-terminal domain
      smart01020
      Location:804 → 915
      B2-adapt-app_C; Beta2-adaptin appendage, C-terminal sub-domain
      sd00044
      Location:78 → 99
      HEAT; HEAT repeat [structural motif]
      pfam01602
      Location:46 → 557
      Adaptin_N; Adaptin N terminal region
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SUS3.1

    Gene LinkOut

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