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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_042850.1 RefSeqGene
- Range
-
5000..203666
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001286658.2 → NP_001273587.1 TBC1 domain family member 4 isoform 2
See identical proteins and their annotated locations for NP_001273587.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks an alternate in-frame exon in the central coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
- Source sequence(s)
-
AB011175, AK307493, AL139230, AL162571, CA448893, FM207107
- Consensus CDS
-
CCDS66564.1
- UniProtKB/TrEMBL
-
A0A3B3IRT3
- Related
- ENSP00000395986.2, ENST00000431480.6
- Conserved Domains (5) summary
-
- smart00164
Location:910 → 1124
- TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
- smart00462
Location:31 → 190
- PTB; Phosphotyrosine-binding domain, phosphotyrosine-interaction (PI) domain
- cd01269
Location:193 → 437
- PTB_TBC1D1_like; TBC1 domain family member 1 and related proteins Phosphotyrosine-binding (PTB) domain
- pfam11830
Location:798 → 856
- DUF3350; Domain of unknown function (DUF3350)
- pfam13094
Location:1191 → 1262
- CENP-Q; CENP-Q, a CENPA-CAD centromere complex subunit
-
NM_001286659.2 → NP_001273588.1 TBC1 domain family member 4 isoform 3
See identical proteins and their annotated locations for NP_001273588.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3, also known as AS160_v2, PMID:18771725) lacks two alternate in-frame exons in the central coding region, compared to variant 1. The encoded isoform (3) is shorter than isoform 1.
- Source sequence(s)
-
AB011175, AK307493, AL139230, AL162571, CA448893, FM207106
- Consensus CDS
-
CCDS66563.1
- UniProtKB/TrEMBL
-
A0A3B3IRT3
- Related
- ENSP00000366852.2, ENST00000377625.6
- Conserved Domains (5) summary
-
- smart00164
Location:855 → 1069
- TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
- smart00462
Location:31 → 190
- PTB; Phosphotyrosine-binding domain, phosphotyrosine-interaction (PI) domain
- cd01269
Location:193 → 437
- PTB_TBC1D1_like; TBC1 domain family member 1 and related proteins Phosphotyrosine-binding (PTB) domain
- pfam11830
Location:743 → 801
- DUF3350; Domain of unknown function (DUF3350)
- pfam13094
Location:1136 → 1207
- CENP-Q; CENP-Q, a CENPA-CAD centromere complex subunit
-
NM_014832.5 → NP_055647.2 TBC1 domain family member 4 isoform 1
See identical proteins and their annotated locations for NP_055647.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
- Source sequence(s)
-
AB011175, AK307493, AL139230, AL162571, CA448893, FM207106
- Consensus CDS
-
CCDS41901.1
- UniProtKB/Swiss-Prot
- A7E2X8, B4DU25, B4E235, B6ETN8, B6ETN9, O60343, Q5W0B9, Q68D14
- UniProtKB/TrEMBL
-
A0A3B3IRT3
- Related
- ENSP00000366863.3, ENST00000377636.8
- Conserved Domains (5) summary
-
- smart00164
Location:918 → 1132
- TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
- smart00462
Location:31 → 190
- PTB; Phosphotyrosine-binding domain, phosphotyrosine-interaction (PI) domain
- cd01269
Location:193 → 437
- PTB_TBC1D1_like; TBC1 domain family member 1 and related proteins Phosphotyrosine-binding (PTB) domain
- pfam11830
Location:806 → 864
- DUF3350; Domain of unknown function (DUF3350)
- pfam13094
Location:1199 → 1270
- CENP-Q; CENP-Q, a CENPA-CAD centromere complex subunit
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000013.11 Reference GRCh38.p14 Primary Assembly
- Range
-
75283503..75482169 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047430811.1 → XP_047286767.1 TBC1 domain family member 4 isoform X6
- UniProtKB/TrEMBL
-
A0A3B3IRT3
-
XM_047430810.1 → XP_047286766.1 TBC1 domain family member 4 isoform X5
- UniProtKB/TrEMBL
-
A0A3B3IRT3
-
XM_011535331.3 → XP_011533633.1 TBC1 domain family member 4 isoform X3
- UniProtKB/TrEMBL
-
A0A3B3IRT3
- Conserved Domains (5) summary
-
- smart00164
Location:881 → 1095
- TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
- smart00462
Location:31 → 190
- PTB; Phosphotyrosine-binding domain, phosphotyrosine-interaction (PI) domain
- cd01269
Location:193 → 437
- PTB_TBC1D1_like; TBC1 domain family member 1 and related proteins Phosphotyrosine-binding (PTB) domain
- pfam11830
Location:769 → 827
- DUF3350; Domain of unknown function (DUF3350)
- pfam13094
Location:1162 → 1233
- CENP-Q; CENP-Q, a CENPA-CAD centromere complex subunit
-
XM_047430809.1 → XP_047286765.1 TBC1 domain family member 4 isoform X4
- UniProtKB/TrEMBL
-
A0A3B3IRT3
- Related
- ENSP00000496983.1, ENST00000648194.1
-
XM_047430808.1 → XP_047286764.1 TBC1 domain family member 4 isoform X2
- UniProtKB/TrEMBL
-
A0A3B3IRT3
-
XM_005266603.3 → XP_005266660.1 TBC1 domain family member 4 isoform X1
- UniProtKB/TrEMBL
-
A0A3B3IRT3
- Conserved Domains (5) summary
-
- smart00164
Location:893 → 1107
- TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
- smart00462
Location:31 → 190
- PTB; Phosphotyrosine-binding domain, phosphotyrosine-interaction (PI) domain
- cd01269
Location:193 → 437
- PTB_TBC1D1_like; TBC1 domain family member 1 and related proteins Phosphotyrosine-binding (PTB) domain
- pfam11830
Location:781 → 839
- DUF3350; Domain of unknown function (DUF3350)
- pfam13094
Location:1174 → 1245
- CENP-Q; CENP-Q, a CENPA-CAD centromere complex subunit
-
XM_006719903.4 → XP_006719966.1 TBC1 domain family member 4 isoform X7
- UniProtKB/TrEMBL
-
A0A3B3IRT3
- Conserved Domains (3) summary
-
- smart00164
Location:760 → 974
- TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
- cd01269
Location:35 → 279
- PTB_TBC1D1_like; TBC1 domain family member 1 and related proteins Phosphotyrosine-binding (PTB) domain
- pfam11830
Location:648 → 706
- DUF3350; Domain of unknown function (DUF3350)
-
XM_047430812.1 → XP_047286768.1 TBC1 domain family member 4 isoform X8
Alternate T2T-CHM13v2.0
Genomic
-
NC_060937.1 Alternate T2T-CHM13v2.0
- Range
-
74507182..74705799 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054375233.1 → XP_054231208.1 TBC1 domain family member 4 isoform X6
- UniProtKB/TrEMBL
-
A0A3B3IRT3
-
XM_054375232.1 → XP_054231207.1 TBC1 domain family member 4 isoform X5
- UniProtKB/TrEMBL
-
A0A3B3IRT3
-
XM_054375230.1 → XP_054231205.1 TBC1 domain family member 4 isoform X3
- UniProtKB/TrEMBL
-
A0A3B3IRT3
-
XM_054375231.1 → XP_054231206.1 TBC1 domain family member 4 isoform X4
- UniProtKB/TrEMBL
-
A0A3B3IRT3
-
XM_054375229.1 → XP_054231204.1 TBC1 domain family member 4 isoform X2
- UniProtKB/TrEMBL
-
A0A3B3IRT3
-
XM_054375228.1 → XP_054231203.1 TBC1 domain family member 4 isoform X1
- UniProtKB/TrEMBL
-
A0A3B3IRT3
-
XM_054375234.1 → XP_054231209.1 TBC1 domain family member 4 isoform X7
- UniProtKB/TrEMBL
-
A0A3B3IRT3
-
XM_054375235.1 → XP_054231210.1 TBC1 domain family member 4 isoform X8