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    ROXY2 Thioredoxin superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831256, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ROXY2
    Official Full Name
    Thioredoxin superfamily protein
    Primary source
    TAIR:AT5G14070
    Locus tag
    AT5G14070
    See related
    Araport:AT5G14070
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MUA22.7; MUA22_7
    Summary
    Encodes glutaredoxin ROXY2. ROXY2, together with ROXY1 (AT3G02000), controls anther development. roxy1 roxy2 double mutants are sterile and do not produce pollen.
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    Genomic context

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    See ROXY2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    1
    Sequence:
    Chromosome: 5; NC_003076.8 (4541780..4542585)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Aspartate kinase family protein Neighboring gene ncRNA Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene regulator of nonsense transcript protein Neighboring gene non-intrinsic ABC protein 14

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ROXY1 and ROXY2, two Arabidopsis glutaredoxin genes, are required for anther development. Xing S, et al. Plant J, 2008 Mar. PMID 18036205
    2. Arabidopsis basic leucine-zipper transcription factors TGA9 and TGA10 interact with floral glutaredoxins ROXY1 and ROXY2 and are redundantly required for anther development. Murmu J, et al. Plant Physiol, 2010 Nov. PMID 20805327, Free PMC Article
    3. Repression of the Arabidopsis thaliana jasmonic acid/ethylene-induced defense pathway by TGA-interacting glutaredoxins depends on their C-terminal ALWL motif. Zander M, et al. Mol Plant, 2012 Jul. PMID 22207719
    4. Extensive signal integration by the phytohormone protein network. Altmann M, et al. Nature, 2020 Jul. PMID 32612234
    5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. TGA9 and TGA10 expression overlaps with ROXY1/2 in developing anthers.
      Title: Arabidopsis basic leucine-zipper transcription factors TGA9 and TGA10 interact with floral glutaredoxins ROXY1 and ROXY2 and are redundantly required for anther development.
    2. Two CC-type glutaredoxins ROXY1 and ROXY2 together control anther development in Arabidopsis thaliana.
      Title: ROXY1 and ROXY2, two Arabidopsis glutaredoxin genes, are required for anther development.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_121410.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within anther development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of DNA-templated transcription IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Thioredoxin superfamily protein
    NP_196911.1
    • ROXY2; FUNCTIONS IN: electron carrier activity, protein disulfide oxidoreductase activity; INVOLVED IN: negative regulation of transcription, anther development; LOCATED IN: cellular_component unknown; EXPRESSED IN: tapetum, floral meristem, hypocotyl, anther, root; CONTAINS InterPro DOMAIN/s: Glutaredoxin-like, plant II (InterPro:IPR011905), Glutaredoxin (InterPro:IPR002109), Thioredoxin fold (InterPro:IPR012335), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: Thioredoxin superfamily protein (TAIR:AT3G02000.1); Has 1062 Blast hits to 1060 proteins in 157 species: Archae - 0; Bacteria - 4; Metazoa - 185; Fungi - 99; Plants - 740; Viruses - 0; Other Eukaryotes - 34 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      4541780..4542585
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_121410.3 → NP_196911.1  Thioredoxin superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196911.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B0FL43, Q8LF89, Q9FMU3
      UniProtKB/TrEMBL
      A0A178UC77, A0A5S9Y4B8
      Conserved Domains (1) summary
      TIGR02189
      Location:37 → 140
      GlrX-like_plant; Glutaredoxin-like family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8LF89.2

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