BETA-VPE beta vacuolar processing enzyme [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: BETA-VPE
Official Full Name: beta vacuolar processing enzyme
Primary source: TAIR:AT1G62710
Locus tag: AT1G62710
See related: Araport:AT1G62710
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: beta vacuolar processing enzyme; BETAVPE; F23N19.7; F23N19_7
Summary: Encodes a vacuolar processing enzyme belonging to a novel group of cysteine proteases that is expressed specifically in seeds and is essential for the proper processing of storage proteins.
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Genomic context

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See BETA-VPE in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 9

Sequence:: Chromosome: 1; NC_003070.9 (23223874..23226983, complement)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

betaVPE is involved in tapetal degradation and pollen development by activating proprotease maturation in Arabidopsis thaliana.
Title: βVPE is involved in tapetal degradation and pollen development by activating proprotease maturation in Arabidopsis thaliana.
Subfamily-Specific Fluorescent Probes for Cysteine Proteases Display Dynamic Protease Activities during Seed Germination.
Title: Subfamily-Specific Fluorescent Probes for Cysteine Proteases Display Dynamic Protease Activities during Seed Germination.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_104948.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables cysteine-type endopeptidase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
involved_in proteolysis involved in protein catabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within vacuolar protein processing	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Component	Evidence Code	Pubs
located_in protein storage vacuole	ISS Inferred from Sequence or Structural Similarity more info
located_in vacuole	ISS Inferred from Sequence or Structural Similarity more info	PubMed

General protein information

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Preferred Names: beta vacuolar processing enzyme

NP_176458.1

beta vacuolar processing enzyme (BETA-VPE); FUNCTIONS IN: cysteine-type endopeptidase activity; INVOLVED IN: proteolysis, response to salt stress, vacuolar protein processing; LOCATED IN: endomembrane system; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase C13, legumain (InterPro:IPR001096); BEST Arabidopsis thaliana protein match is: gamma vacuolar processing enzyme (TAIR:AT4G32940.1); Has 785 Blast hits to 783 proteins in 241 species: Archae - 4; Bacteria - 10; Metazoa - 274; Fungi - 115; Plants - 253; Viruses - 0; Other Eukaryotes - 129 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

23223874..23226983 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_104948.4 → NP_176458.1 beta vacuolar processing enzyme [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_176458.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q39044, Q93VS7, Q9SI79

UniProtKB/TrEMBL

A0A178W0Z7, A0A5S9WPC5

Conserved Domains (2) summary

pfam01650
Location:51 → 323

Peptidase_C13; Peptidase C13 family

cd21115
Location:348 → 467

legumain_C; C-terminal prodomain of legumain